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Antimalarial Chemotherapy

Mechanisms of Action, Resistance, and New Directions in Drug Discovery

  • Book
  • © 2001

Overview

Editors:
  1. Philip J. Rosenthal

    1. School of Medicine, University of California, San Francisco, USA

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Part of the book series: Infectious Disease (ID)

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Table of contents (20 chapters)

  1. New Compounds, New Approaches, and New Targets

    1. Iron Chelators

      • Mark Loyevsky, Victor R. Gordeuk
      Pages 307-324

    2. Protease Inhibitors

      • Philip J. Rosenthal
      Pages 325-345

    3. Inhibitors of Phospholipid Metabolism

      • Henri Joseph Vial, Michèle Calas
      Pages 347-365

    4. Development of New Malaria Chemotherapy by Utilization of Parasite-Induced Transport

      • Annette M. Gero, Alexander L. Weis
      Pages 367-384

  2. Back Matter

    Pages 385-396
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Keywords

About this book

Philip Rosenthal, MD, and a panel of leading malaria experts drawn from academia, the military, and international health organizations survey the latest scientific understanding of antimalarial chemotherapy, emphasizing the molecular mechanisms of resistance and the description of important new targets. Their survey covers the current status of malarial and antimalarial chemotherapy, the relevant biology and biochemistry of malaria parasites, the antimalarial drugs currently available, new chemical approaches to chemotherapy, and possible new targets for chemotherapy. Comprehensive and cutting-edge, Antimalarial Chemotherapy: Mechanisms of Action, Resistance, and New Directions in Drug Discovery clearly delineates all the basic and clinical research now addressing one of the world's major unresolved disease problems, work that is now powerfully driving the rapid pace of antimalarial drug discovery today.

Reviews

"With contributions from 41 different authors, this book provides a welcome collection of short reviews covering numerous topics in antimalarial chemotherapy. ...this book will offer a useful review for those who study malaria and, more importantly, an entry point into antimalarial chemotherapy for those new in the field." - Journal of Medicinal Chemistry

"...the publication of a new on antimalarial chemotheraphy is very topcial and timely. Philip Rosenthal has put together a very comprehensive book on the current status of research in this important field of medicianl chemistry....The part on established antimalarial drugs covers all drugs currently in clinical application and trials....Special emphasis is put in many articles on aspects of toxicity, therapy, problems, and future developments....the editor has managed to compile the contributions in such a way that a comprehensive picture of the current status emerges and the book feels more like a single-author publication than an edited work....The book is a must for chemists, biologists, and health professionals involved in malaria research." - ChemBioChem

"...thought provoking with its new leads to drug discovery...an essential addition to the libraries and an essential reading book for malariologists." -The National Journal of India

Editors and Affiliations

  • School of Medicine, University of California, San Francisco, USA

    Philip J. Rosenthal

Bibliographic Information

  • Book Title: Antimalarial Chemotherapy

  • Book Subtitle: Mechanisms of Action, Resistance, and New Directions in Drug Discovery

  • Editors: Philip J. Rosenthal

  • Series Title: Infectious Disease

  • DOI: https://doi.org/10.1007/978-1-59259-111-4

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 2001

  • Hardcover ISBN: 978-0-89603-670-3Published: 01 April 2001

  • Softcover ISBN: 978-1-61737-124-0Published: 19 November 2010

  • eBook ISBN: 978-1-59259-111-4Published: 01 April 2001

  • Edition Number: 1

  • Number of Pages: XI, 396

  • Topics: Infectious Diseases

  • Industry Sectors: Biotechnology, Health & Hospitals, Pharma

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