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DNA Damage and Repair

Advances from Phage to Humans

  • Jac A. Nickoloff
  • Merl F. Hoekstra

Part of the Contemporary Cancer Research book series (CCR)

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Carol Bernstein, Harris Bernstein
    Pages 1-19
  3. Steven J. Sandler
    Pages 21-42
  4. Phyllis R. Strauss, Noreen E. O’Regan
    Pages 43-85
  5. Ian D. Hickson, Michael A. Gorman, Paul S. Freemont
    Pages 87-105
  6. John H. J. Petrini, Richard S. Maser, Debra A. Bressan
    Pages 147-172
  7. Mark A. Brenneman
    Pages 237-267
  8. Lauryl M. J. Nutter, Chrystal K. Palaty, Martin Nemec, Cynthia J. Guidos, Jayne S. Danska
    Pages 269-313
  9. Troy Fiddler, Jing Huang, Elizabeth Ostermeyer, Teresa Johnson-Pais, Mathew J. Thayer
    Pages 315-328
  10. Colin A. Bill, Jac A. Nickoloff
    Pages 329-357
  11. Susan M. Bailey, Julianne Meyne, Edwin H. Goodwin
    Pages 359-375
  12. Alan R. Lehmann, Elaine M. Taylor
    Pages 377-401
  13. Back Matter
    Pages 403-411

About this book

Introduction

In recent years it has become increasingly apparent that DNA repair processes play key roles in protecting genome integrity, where the failure of repair systems is directly responsible for many, if not the majority of, cancers. In DNA Damage and Repair, Vol. III: Advances from Phage to Humans, Jac A. Nickoloff and Merl F. Hoekstra update and expand their two earlier acclaimed volumes (Vol. I: DNA Repair in Prokaryotes and Lower Eukaryotes and Vol. II: DNA Repair in Higher Eukaryotes) with cutting-edge reviews by leading authorities of primary experimental findings about DNA repair processes in cancer biology. The reviews cover a wide range of topics from viruses and prokaryotes to higher eukaryotes, and include several new topics, among them the role of recombination in replication of damaged DNA, X-ray crystallographic analysis of DNA repair protein structures, DNA repair proteins and teleomere function, and the roles of BRCA1 and BRCA2 in DNA repair. The contributors make every effort to integrate the basic experimental information with clinical aspects of cancer biology as they relate to DNA repair.
Authoritative and up-to-date, DNA Damage and Repair, Vol. III: Advances from Phage to Humans surveys the rapidly moving research in DNA damage and repair, offering broad integrated coverage that will help researchers understand the important functional relationships among different DNA repair pathways, as well as the relationships among DNA repair pathways, cancer etiology, and cancer therapies.

Keywords

DNA DNA replication Telomere conservation prokaryotes recombination saccharomyces cerevisiae

Editors and affiliations

  • Jac A. Nickoloff
    • 1
  • Merl F. Hoekstra
    • 2
  1. 1.Department of Molecular Genetics and MicrobiologyUniversity of New Mexico School of MedicineAlbuquerqueUSA
  2. 2.QbiogeneCarlsbadUSA

Bibliographic information

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