Human Growth Hormone

Research and Clinical Practice

  • Roy G. Smith
  • Michael O. Thorner

Part of the Contemporary Endocrinology book series (COE, volume 19)

Table of contents

  1. Front Matter
    Pages i-x
  2. Overview of Human Growth Hormone

    1. Roy G. Smith
      Pages 1-13
  3. Research

    1. Front Matter
      Pages 15-15
    2. C. Y. Bowers
      Pages 17-43
    3. Arthur A. Patchett, Matthew J. Wyvratt
      Pages 45-67
    4. Andrew D. Howard, Scott D. Feighner, Roy G. Smith, Lex H. T. Van der Ploeg
      Pages 69-84
    5. Gurkeerat Singh, George Liapakis, Terry Reisine
      Pages 109-117
    6. David Brown, Elinor A. Stephens, Gareth Leng, Roy G. Smith
      Pages 119-130
    7. Kenneth H. Pearce, James A. Wells
      Pages 131-143
    8. Pamela A. Bennett, Iain C. A. F. Robinson
      Pages 145-166
  4. Clinical Practice

    1. Front Matter
      Pages 167-167
    2. Linda Anne DiMeglio, Paul L. Hofman, Ora Hirsch Pescovitz
      Pages 169-190
    3. Barry B. Bercu, Howard J. Heinze
      Pages 191-219
    4. Paul V. Carroll, Emanuel R. Christ, Peter H. Sönksen
      Pages 221-232
    5. Howard B. A. Baum, Anne Klibanski
      Pages 233-245
    6. Gudmundur Johannsson, Per Mårin, Jan-Ove Johansson, Bengt Åke Bengtsson
      Pages 247-260
    7. Eve Van Cauter, Georges Copinschi
      Pages 261-283
    8. Kathleen Mulligan, Morris Schambelan
      Pages 285-295
    9. George R. Merriam, Fernando Cassorla
      Pages 297-313
    10. Mark A. Bach, Glenn J. Gormley
      Pages 315-334
  5. Back Matter
    Pages 335-348

About this book


In Human Growth Hormone: Research and Clinical Ptractice, Roy Smith and a distinguished panel of researchers and clinicians combine a review of GH regulation and its action at the molecular level with a state-of-the-art description of the basis for GH deficiency and the use of GH therapy in a variety of clinical situations. The clinical uses of GH discussed here move beyond the treatment of GH-deficient children to include the genetics of GH-deficiency, GH-deficiency in adults, osteoporosis, Syndrome X, sleep quality, GH in AIDS patients, and GHRH in clinical studies. Also described are a family of GH-secretagogues that bind to a new orphan receptor controlling the physiology of GH release. The discussion of the new GH therapeutics includes their design, their action as regulators in the pituitary gland and in the central nervous system, and their use as new agents for treating growth hormone deficiency states.

Human Growth Hormone: Research and Clinical Practice offers an unprecedented cutting-edge synthesis of basic science and clinical practice. Timely and innovative, this book will benefit both basic and clinical researchers, as well as those clinical endocrinologists who want to use growth hormone not only in treating children, but also in treating adult disorders, including those associated with metabolic disease.


growth growth hormone hormone

Editors and affiliations

  • Roy G. Smith
    • 1
  • Michael O. Thorner
    • 2
  1. 1.Huffington Center on Aging and Department of Cell BiologyBaylor College of MedicineHoustonUSA
  2. 2.Department of MedicineUniversity of Virginia Health Sciences CenterCharlottesvilleUSA

Bibliographic information

Industry Sectors
Health & Hospitals
Internal Medicine & Dermatology