© 2019

Chiral Separations

Methods and Protocols

  • Gerhard K. E. Scriba

Part of the Methods in Molecular Biology book series (MIMB, volume 1985)

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Rituraj Dubey, Ravi Bhushan
    Pages 35-44
  3. Sheng-Ming Xie, Jun-Hui Zhang, Li-Ming Yuan
    Pages 45-55
  4. Lushan Yu, Shengjia Wang, Su Zeng
    Pages 81-91
  5. Liang Zhao, Hui Li, Shuqing Dong, Yanping Shi
    Pages 171-181
  6. Garrett Hellinghausen, Daniel W. Armstrong
    Pages 183-200
  7. Federica Ianni, Lucia Pucciarini, Andrea Carotti, Roccaldo Sardella, Benedetto Natalini
    Pages 279-302

About this book


This detailed book focuses on analytical separations by chromatographic and electrophoretic techniques, providing some overview along with numerous practically-oriented applications of the most important analytical techniques in chiral separation sciences. While some compounds may only be enantioseparated with one technique based on the physico-chemical properties, often the analyst can choose between two or more analytical techniques for a given analyte, which requires knowledge of the strengths and weaknesses of each technique in order to select the most appropriate method for the given problem. This collection binds that knowledge in one volume. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. 

Authoritative and practical, Chiral Separations: Methods and Protocols, Third Edition serves as a helpful guide for analytical chemists working on stereochemical problems in the fields of pharmacy, chemistry, biochemistry, food chemistry, molecular biology, forensics, environmental sciences, or cosmetics in academia, government, or industry.


Liquid Chromatography Electrophoretic techniques Enantioseparations Chiral compounds Enantiomers Analytical separations

Editors and affiliations

  • Gerhard K. E. Scriba
    • 1
  1. 1.Department of Pharmaceutical ChemistryUniversity of JenaJenaGermany

Bibliographic information

  • Book Title Chiral Separations
  • Book Subtitle Methods and Protocols
  • Editors Gerhard K.E. Scriba
  • Series Title Methods in Molecular Biology
  • DOI
  • Copyright Information Springer Science+Business Media, LLC, part of Springer Nature 2019
  • Publisher Name Humana, New York, NY
  • eBook Packages Springer Protocols
  • Hardcover ISBN 978-1-4939-9437-3
  • Softcover ISBN 978-1-4939-9440-3
  • eBook ISBN 978-1-4939-9438-0
  • Series ISSN 1064-3745
  • Series E-ISSN 1940-6029
  • Edition Number 3
  • Number of Pages XIV, 487
  • Number of Illustrations 91 b/w illustrations, 56 illustrations in colour
  • Topics Pharmaceutical Sciences/Technology
    Analytical Chemistry
    Biochemistry, general
  • Buy this book on publisher's site
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“The book is aimed at investigators in any discipline working in the field of chirality. It will be of special interest to anyone who has a need to separate chiral molecules. … Detailed protocols are provided for the systems covered in the book that will make it easier for investigators wishing to replicate one of these procedures.” (Thomas J. Wenzel, Analytical and Bioanalytical Chemistry, Vol. 411, 2019)