Nanotechnology for Nucleic Acid Delivery

Methods and Protocols

  • Manfred Ogris
  • Haider Sami

Part of the Methods in Molecular Biology book series (MIMB, volume 1943)

Table of contents

  1. Front Matter
    Pages i-xv
  2. Ye-Zi You, Jun-Jie Yan, Fei Yu, Zhi-Qiang Yu, David Oupicky
    Pages 27-38
  3. Antoine Kichler, A. James Mason, Arnaud Marquette, Burkhard Bechinger
    Pages 39-59
  4. Wolfgang Rödl, Alexander Taschauer, David Schaffert, Ernst Wagner, Manfred Ogris
    Pages 83-99
  5. Manon Ripoll, Patrick Neuberg, Jean-Serge Remy, Antoine Kichler
    Pages 101-122
  6. Michaela Guter, Miriam Breunig
    Pages 153-160
  7. Lingxiao Xie, Yi Zou, Sean Carroll, Maria Muniz, Guangzhao Mao
    Pages 161-176
  8. Angela K. Pannier, Tyler Kozisek, Tatiana Segura
    Pages 177-197
  9. Yi Zou, Lei Wan, Jenifer Blacklock, Lingxiao Xie, Sean Carroll, David Oupicky et al.
    Pages 199-209
  10. Julia Christina Kasper, Sarah Hedtrich, Wolfgang Friess
    Pages 211-225
  11. Heleen Dewitte, Silke Roovers, Stefaan C. De Smedt, Ine Lentacker
    Pages 241-251
  12. Dialechti Vlaskou, Olga Mykhaylyk, Christian Plank
    Pages 253-290
  13. Ladan Parhamifar, Helene Andersen, S. Moein Moghimi
    Pages 291-299
  14. Claire Rome, Julien Gravier, Marie Morille, Gilles Divita, Anne-Laure Bolcato-Bellemin, Véronique Josserand et al.
    Pages 347-363
  15. Olivia M. Merkel, Leigh M. Marsh, Holger Garn, Thomas Kissel
    Pages 365-375
  16. Nathalie Mignet, Corinne Marie, Anthony Delalande, Simona Manta, Michel-Francis Bureau, Gilles Renault et al.
    Pages 377-387
  17. Mark D. Zabel, Luke Mollnow, Heather Bender
    Pages 389-403
  18. Back Matter
    Pages 405-406

About this book


This detailed second edition volume expands upon the prior edition by addressing newly emerged technologies as well as improved existing protocols in nucleic acid delivery via nanotechnology. The book addresses topics ranging from chemical synthesis of macromolecules and bioconjugates, novel and established nanoformulations, characterization of these nanoformulations for biophysical, biological and toxicological aspects, and also protocols dealing with application and imaging of such carrier systems in vivo. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective chapters, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. 

Authoritative and up-to-date, Nanotechnology for Nucleic Acid Delivery: Methods and Protocols, Second Edition serves as an ideal guide to researchers seeking to use this vital area of study in their own lab work or to progress knowledge within the field itself.


Delivery systems Toxicology Bioconjugates Nanocarriers Nanoformulations Nucleic acid therapies Biocompatibility and toxicity Carrier systems

Editors and affiliations

  • Manfred Ogris
    • 1
  • Haider Sami
    • 2
  1. 1.Laboratory of MacroMolecular Cancer Therapeutics (MMCT), Department of Pharmaceutical Chemistry, Center of Pharmaceutical Sciences, Faculty of Life SciencesUniversity of ViennaViennaAustria
  2. 2.Laboratory of MacroMolecular Cancer Therapeutics (MMCT), Department of Pharmaceutical Chemistry, Center of Pharmaceutical Sciences, Faculty of Life SciencesUniversity of ViennaViennaAustria

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media, LLC, part of Springer Nature 2019
  • Publisher Name Humana Press, New York, NY
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-4939-9091-7
  • Online ISBN 978-1-4939-9092-4
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site
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