Brain-Derived Neurotrophic Factor (BDNF)

  • Carlos B. Duarte
  • Enrico Tongiorgi

Part of the Neuromethods book series (NM, volume 143)

Table of contents

  1. Front Matter
    Pages i-xii
  2. Introduction

  3. Transcripts of BDNF

    1. Front Matter
      Pages 11-11
    2. Andrea Colliva, Kristen R. Maynard, Keri Martinowich, Enrico Tongiorgi
      Pages 27-53
    3. Chinnavuth Vatanashevanopakorn, Amit Grover, Arup R. Nath, Kevin Clark, Paul Sopp, Claus Nerlov et al.
      Pages 55-76
  4. Protein Forms of BDNF

    1. Front Matter
      Pages 87-87
    2. Tanja Brigadski, Petra Lichtenecker, Volkmar Lessmann
      Pages 119-129
  5. Receptors of BDNF

    1. Front Matter
      Pages 131-131
    2. Chiara Salio, Adalberto Merighi
      Pages 133-148
    3. Charles E. Hall, James O. McNamara, Ryohei Yasuda
      Pages 149-157
  6. Signaling Cascades of BDNF

    1. Front Matter
      Pages 159-159
    2. João R. Gomes, Andrea Lobo, Carlos B. Duarte, Mário Grãos
      Pages 161-183
    3. Rui O. Costa, Tânia Perestrelo, Diogo Tomé, Ramiro D. Almeida
      Pages 185-201
  7. BDNF-Induced Protein Synthesis and Synaptic Regulation

  8. Back Matter
    Pages 257-258

About this book


This volume discusses the latest techniques and methodologies used in the neurotrophin field to study the physiology of the Brain-Derived Neurotrophic Factor (BDNF). The book provides the tools essential to any researcher that intends to explore the peculiar regulation of this neurotrophin from gene expression to its release and the signaling by TrkB receptors, as well as to study the neuronal responses to BDNF or the role of neurotrophin in various neurological diseases. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory.

Cutting edge and comprehensive, Brain-Derived Neurotrophic Factor(BDNF) is a valuable resource for researchers who want to further study the diversity of physiological roles of this important growth factor.


gene expression cultured neurons TrkB receptors FRET sensors endocytic sorting

Editors and affiliations

  • Carlos B. Duarte
    • 1
  • Enrico Tongiorgi
    • 2
  1. 1.Center for Neuroscience and Cell Biology and Department of Life SciencesUniversity of CoimbraCoimbraPortugal
  2. 2.BRAIN Center for Neuroscience, Department of Life SciencesUniversity of TriesteTriesteItaly

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media, LLC, part of Springer Nature 2019
  • Publisher Name Humana, New York, NY
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-4939-8969-0
  • Online ISBN 978-1-4939-8970-6
  • Series Print ISSN 0893-2336
  • Series Online ISSN 1940-6045
  • Buy this book on publisher's site
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