Blood-Brain Barrier

  • Tatiana Barichello

Part of the Neuromethods book series (NM, volume 142)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Tatiana Barichello, Allan Collodel, Rodrigo Hasbun, Rodrigo Morales
    Pages 1-8
  3. Brian M. Kopec, Kavisha R. Ulapane, Mario E. G. Moral, Teruna J. Siahaan
    Pages 9-43
  4. Mohammad A. Kaisar, Vinay V. Abhyankar, Luca Cucullo
    Pages 55-70
  5. Charles T. Spencer, Mireya G. Ramos Muniz
    Pages 137-161
  6. Cameron R. Love, Brigitte Dauwalder
    Pages 175-185
  7. Fabricia Petronilho, Julia L. Goldman, Tatiana Barichello
    Pages 197-203
  8. Isabel Gonçalves, Telma Quintela, Ana Catarina Duarte, Peter Hubbard, Graça Baltazar, Christian Schwerk et al.
    Pages 205-230
  9. Yoshiyuki Kubo, Shin-ichi Akanuma, Ken-ichi Hosoya
    Pages 249-265
  10. Dallan McMahon, Charissa Poon, Kullervo Hynynen
    Pages 267-297
  11. Aline Silva de Miranda, Thiago Macedo Cordeiro, Milene Alvarenga Rachid, Antônio Lúcio Teixeira
    Pages 315-327
  12. Vijayasree V. Giridharan, Tatiana Barichello, Sudhakar Selvaraj
    Pages 329-342
  13. Pavani Sayana, Jean Pierre Oses, Tatiana Barichello, Vijayasree V. Giridharan
    Pages 343-363
  14. Back Matter
    Pages 365-367

About this book


This volume focuses on experimental research with applicable models to study physiology, biochemistry, and molecular biology of the blood-brain barrier (BBB). This book is organized into six parts: Part One is an overview of the physiology of BBB; Part Two explores in vitro cell models to study the BBB; Part Three discusses techniques in vivo and ex vivo models to evaluate BBB in Drosophila melanogaster, Zebrafish, and rodents; Part Four looks at permeability, influx, efflux transportation, and drug delivery through the BBB; Part Five talks about various invasive and non-invasive imaging techniques to study BBB; and Part Six describes how molecular biomarkers are used to look at the integrity or dysfunction of the BBB. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. 

Cutting-edge and thorough, Blood-Brain Barrier is a valuable resource to aid both novice and experienced investigators with performing experiments using new and classic translational approaches.


Neuronal progenitor cell TEER Sodium fluorescein choroid plexuses drug transport

Editors and affiliations

  • Tatiana Barichello
    • 1
  1. 1.Department of Psychiatry & Behavioral SciencesThe University of Texas Health Science Center at Houston (UTHealth)HoustonUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media, LLC, part of Springer Nature 2019
  • Publisher Name Humana Press, New York, NY
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-4939-8945-4
  • Online ISBN 978-1-4939-8946-1
  • Series Print ISSN 0893-2336
  • Series Online ISSN 1940-6045
  • Buy this book on publisher's site
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