LC-MS in Drug Analysis

Methods and Protocols

  • Loralie J. Langman
  • Christine L.H. Snozek

Part of the Methods in Molecular Biology book series (MIMB, volume 1872)

Table of contents

  1. Front Matter
    Pages i-x
  2. Christine L. H. Snozek, Loralie J. Langman, Steven W. Cotten
    Pages 1-10
  3. Olaf H. Drummer, Matthew Di Rago, Dimitri Gerostamoulos
    Pages 23-39
  4. Darlington Danso, Loralie J. Langman, Paul J. Jannetto
    Pages 41-50
  5. Andrea R. Terrell, Vipin Adhlakha, Poluru Reddy
    Pages 51-59
  6. He Sarina Yang, Leslie Edinboro
    Pages 67-73
  7. Geoffrey S. Rule, Alan L. Rockwood, Kamisha L. Johnson-Davis
    Pages 75-83
  8. Gabrielle N. Winston-McPherson, Michael Schmeling, Andrew N. Hoofnagle
    Pages 101-110
  9. Matthew W. Bjergum, Paul J. Jannetto, Loralie J. Langman
    Pages 111-118
  10. Sherri L. Kacinko, Donna M. Papsun
    Pages 129-135
  11. Piotr Adamowicz, Bogdan Tokarczyk
    Pages 165-180
  12. Kendra L. Palmer, Matthew D. Krasowski
    Pages 191-197
  13. Cynthia A. Coulter, Christine M. Moore
    Pages 237-259
  14. Back Matter
    Pages 273-274

About this book


This second edition provides detailed LC-MS(/MS) procedures for the analysis of compounds of clinical and toxicological significance. Chapters detail new and updated methods for analyzing drugs focusing on advances in technology, alternate matrices, and rapidly-changing classes of drugs of abuse, compounds pertinent to toxicology, and therapeutic agents. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and cutting-edge, LC-MS in Drug Analysis: Methods and Protocols, Second Edition aims to ensure successful results in the further study of this vital field.


Chromatography Drug quantitation Drugs of abuse Toxic compounds Therapeutic agents Liquid chromatography–mass spectrometry

Editors and affiliations

  • Loralie J. Langman
    • 1
  • Christine L.H. Snozek
    • 2
  1. 1.Department of Laboratory, Medicine and PathologyMayo ClinicRochesterUSA
  2. 2.Department of Laboratory, Medicine and PathologyMayo Clinic in ArizonaScottsdaleUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media, LLC, part of Springer Nature 2019
  • Publisher Name Humana Press, New York, NY
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-4939-8822-8
  • Online ISBN 978-1-4939-8823-5
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals
Pharmacology & Toxicology
Consumer Packaged Goods