Functional Proteomics

Methods and Protocols

  • Xing Wang
  • Matthew Kuruc

Part of the Methods in Molecular Biology book series (MIMB, volume 1871)

Table of contents

  1. Front Matter
    Pages i-xii
  2. Ray C. Perkins
    Pages 1-40
  3. Choo Hock Tan, Kae Yi Tan, Nget Hong Tan
    Pages 83-92
  4. Rodrigo García-Valiente, Jonatan Fernández-García, Javier Carabias-Sánchez, Alicia Landeira-Viñuela, Rafael Góngora, María Gonzalez-Gonzalez et al.
    Pages 107-122
  5. Lisa A. Lai, Zachary Tong, Ru Chen, Sheng Pan
    Pages 123-132
  6. Youcef Shahali, Hélène Sénéchal, Pascal Poncet
    Pages 133-141
  7. Peipei Li, Yuan Meng, Li Wang, Li-jun Di
    Pages 143-151
  8. Tina R. Tuveng, Vincent G. H. Eijsink, Magnus Ø. Arntzen
    Pages 159-177
  9. Sneha M. Pinto, Yashwanth Subbannayya, T. S. Keshava Prasad
    Pages 197-224
  10. Yun Chen, Liang Liu
    Pages 265-277
  11. Sandrine Aros-Calt, Florence A. Castelli, Patricia Lamourette, Gaspard Gervasi, Christophe Junot, Bruno H. Muller et al.
    Pages 279-293
  12. Christopher A. Toth, Zsuzsanna Kuklenyik, John R. Barr
    Pages 295-311
  13. Ingrid M. Verhamme, Sarah E. Leonard, Ray C. Perkins
    Pages 313-392
  14. Youcef Shahali, Hélène Sénéchal, Pascal Poncet
    Pages 393-403
  15. Haili Li, Keren Byrne, Crispin A. Howitt, Michelle L. Colgrave
    Pages 405-412
  16. Hongye Wang, Zheng Cao, Hu Duan, Xiaobo Yu
    Pages 413-420
  17. Alba Hykollari, Daniel Malzl, Iain B. H. Wilson, Katharina Paschinger
    Pages 421-435
  18. Sami Pietilä, Tomi Suomi, Juhani Aakko, Laura L. Elo
    Pages 455-465
  19. Back Matter
    Pages 467-477

About this book


This book seeks to fill in the current technology gap with a specific collection of technologies developed for the study of protein function at a proteome scale. Chapters explore topics from protein functions to other aspects of protein analysis, especially in post-translational modification, as most proteomes use this mechanism in some capacity to carry out their unique role in cellular regulation. By comparing functional proteomes, this presents a bridge to other levels of system biology research including genomics and metabolomics in order to provide readers with a relatively complete picture for how one might study the biological system of their interest. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and cutting-edge, Functional Proteomics: Methods and Protocols collects these novel technologies in the hope that new frontiers in biological research will be created, important drug targets can be identified, and clinically validated biomarkers and diagnostic tests can be further developed.


Protein functional analysis Proteome scale Drug development Post-translational modification Systems biology Biomarker validation

Editors and affiliations

  • Xing Wang
    • 1
  • Matthew Kuruc
    • 2
  1. 1.Array Bridge Inc.St. LouisUSA
  2. 2.Biotech Support Group LLCMonmouth JunctionUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media, LLC, part of Springer Nature 2019
  • Publisher Name Humana Press, New York, NY
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-4939-8813-6
  • Online ISBN 978-1-4939-8814-3
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site
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