Rheumatoid Arthritis

Methods and Protocols

  • Shuang Liu

Part of the Methods in Molecular Biology book series (MIMB, volume 1868)

Table of contents

  1. Front Matter
    Pages i-ix
  2. Animal Models

    1. Front Matter
      Pages 1-1
    2. Maya Miyoshi, Shuang Liu
      Pages 3-7
    3. Shuang Liu
      Pages 9-15
    4. Shuang Liu, Maya Miyoshi
      Pages 17-22
    5. Maya Miyoshi, Shuang Liu
      Pages 23-28
    6. Takeshi Kiyoi
      Pages 29-39
    7. Shuang Liu, Erika Takemasa
      Pages 41-45
  3. Therapeutic Approach

    1. Front Matter
      Pages 47-47
    2. Yasuyuki Suzuki
      Pages 69-77
    3. Erika Takemasa, Shuang Liu, Hitoshi Hasegawa
      Pages 79-92
    4. Shuang Liu, Yasuyuki Suzuki, Makoto Inui
      Pages 113-121
    5. Shuang Liu
      Pages 123-128
    6. Shuang Liu
      Pages 129-135
    7. Shuang Liu
      Pages 145-150
  4. Evaluation of Immunological Status

    1. Front Matter
      Pages 151-151
    2. Erika Takemasa, Shuang Liu
      Pages 153-159
    3. Shuang Liu
      Pages 161-168
    4. Shuang Liu, Miyuki Kuno
      Pages 169-176
    5. Saho Maruyama
      Pages 177-199
    6. Shuang Liu
      Pages 209-213
    7. M. Mogi, Shuang Liu
      Pages 223-232
  5. Clinical Approach

    1. Front Matter
      Pages 233-233
    2. Hitoshi Hasegawa
      Pages 235-241
  6. Back Matter
    Pages 251-253

About this book


This volume provides a summary of the standard laboratory protocols and methodology commonly used in basic and translational studies in the field of rheumatoid arthritis (RA) treatment. Chapters detail including basic RA models, evaluation of disease activity and immunological status, systemic drug delivery, and new research tools. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

 Authoritative and cutting-edge, Rheumatoid Arthritis: Methods and Protocols aims to be a basic manual for clinical researchers who are just getting started in the field of intervention study.


Autoimmune inflammation Viral-mediated gene therapy Drug development Functional antibodies Aptamers

Editors and affiliations

  • Shuang Liu
    • 1
  1. 1.Department of PharmacologyEhime University Graduate School of MedicineToonJapan

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media, LLC, part of Springer Nature 2018
  • Publisher Name Humana Press, New York, NY
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-4939-8801-3
  • Online ISBN 978-1-4939-8802-0
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site
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