Methods and Protocols

  • Alexandra Lucas

Part of the Methods in Molecular Biology book series (MIMB, volume 1826)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Alexandra Lucas, Jordan R. Yaron, Liqiang Zhang, Sriram Ambadapadi
    Pages 1-7
  3. Lucas R. de Souza, Benjamin M. Scott, Varsha Bhakta, David A. Donkor, Darian L. Perruzza, William P. Sheffield
    Pages 41-64
  4. Jordan R. Yaron, Sriram Ambadapadi, Liqiang Zhang, Alexandra Lucas
    Pages 65-71
  5. Masmudur M. Rahman
    Pages 73-86
  6. Emma L. K. Elliston, David A. Lomas, James A. Irving
    Pages 87-107
  7. Annamaria Fra, Emanuela D’Acunto, Mattia Laffranchi, Elena Miranda
    Pages 109-121
  8. Felix C. Wahlmüller, Judit Mihaly-Bison, Margarethe Geiger
    Pages 123-132
  9. Liqiang Zhang, Jordan R. Yaron, Sriram Ambadapadi, Alexandra Lucas
    Pages 133-142
  10. Sihong Song, Yuanqing Lu, Ahmed S. Elshikha
    Pages 143-155
  11. Hao Chen, Sriram Ambadapadi, Erbin Dai, Liying Liu, Jordan R. Yaron, Liqiang Zhang et al.
    Pages 157-182
  12. Subhradip Mukhopadhyay, Tierra A. Johnson, Rajabrata Sarkar, Toni M. Antalis
    Pages 197-211
  13. Juan Maldonado, Jordan R. Yaron, Liqiang Zhang, Alexandra Lucas
    Pages 213-221
  14. Alexandra Lucas, Jordan R. Yaron, Liqiang Zhang, Colin Macaulay, Grant McFadden
    Pages 255-265
  15. Back Matter
    Pages 267-276

About this book


This volume explores the latest methods used to study and define serpin molecular structure, basic protease inhibition, serpin targets, and the roles of serpin in biology and disease using animal models. The chapters in this book cover topics such as crystallography and phage display, peptide design, phospholipid binding, and thrombus formation to microbiome analysis and development. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Cutting edge and authoritative, Serpins: Methods and Protocols is a valuable resource for researchers and scientists interested in learning more about this evolving field.


Serine protease inhibitors Regulatory drugs Inhibitory agents Therapeutic design Enzyme inhibition assays drug development therapeutics

Editors and affiliations

  • Alexandra Lucas
    • 1
  1. 1.Biodesign Center for Personalized Diagnostics and Center for Immunotherapy Vaccines and VirotherapyArizona State UniversityTempeUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media, LLC, part of Springer Nature 2018
  • Publisher Name Humana Press, New York, NY
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-4939-8644-6
  • Online ISBN 978-1-4939-8645-3
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site
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