Thyroid Hormone Nuclear Receptor

Methods and Protocols

  • Michelina Plateroti
  • Jacques Samarut

Part of the Methods in Molecular Biology book series (MIMB, volume 1801)

Table of contents

  1. Front Matter
    Pages i-xii
  2. Hung-Yun Lin, Shaker A. Mousa, Paul J. Davis
    Pages 61-65
  3. Antonio C. Bianco, Rodrigo R. da Conceição
    Pages 67-83
  4. J. H. Duncan Bassett, Graham R. Williams
    Pages 123-154
  5. Chantal Wrutniak-Cabello, François Casas, Gérard Cabello
    Pages 163-181
  6. Bilal B. Mughal, Barbara A. Demeneix, Jean-Baptiste Fini
    Pages 183-192
  7. Jordan Devereaux, Skylar J. Ferrara, Thomas S. Scanlan
    Pages 193-206
  8. Xuguang Zhu, Sheue-Yann Cheng
    Pages 207-223
  9. C. Briet, Natacha Bouhours-Nouet, F. Illouz, D. Prunier-Mirebeau, P. Rodien
    Pages 241-245
  10. Liezhen Fu, Luan Wen, Yun-Bo Shi
    Pages 247-263
  11. Nicolas Buisine, Gwenneg Kerdivel, Laurent M. Sachs
    Pages 265-285
  12. Federica Marelli, Luca Persani
    Pages 287-298
  13. Back Matter
    Pages 299-300

About this book


This volume aims to detail the advances in the field of Thyroid hormones (THs), namely T3 and T4, and their nuclear receptor TRs from a conceptual and methodological point of view. Chapters guide readers through a general introduction, TR's engineered mice, human genetics of TRs, control of the hypothalamus-pituitary-thyroid (HPT) axis, the relevance of the local THs production and metabolism and pathological consequences of TH/TR alterations. Non-mammalian models are also presented and discussed. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.


Authoritative and practical, Thyroid Hormone Nuclear Receptor: Methods and Protocols aims to ensure successful results in the further study of this vital field.


epidemiology transcriptome radioactive iodine. deep sequencing epigenetics

Editors and affiliations

  • Michelina Plateroti
    • 1
  • Jacques Samarut
    • 2
  1. 1.Centre Léon BérardCancer Research Center of LyonLyonFrance
  2. 2.École normale supérieure de LyonLyonFrance

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media, LLC, part of Springer Nature 2018
  • Publisher Name Humana Press, New York, NY
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-4939-7901-1
  • Online ISBN 978-1-4939-7902-8
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site
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