Table of contents
Systems Biology of the Cancer Genetic and Epigenetic Landscape
Systems Analyses of Signaling Networks in Cancer Cells
Systems Analysis of Cancer Cell Metabolism
Systems Biology of Metastasis and Tumor/Microenvironment Interactions
Modeling Drug Responses in Cancer Cells
About this book
This book comprises protocols describing systems biology methodologies and computational tools, offering a variety of ways to analyze different types of high-throughput cancer data. Chapters give an overview over data types available in large-scale data repositories and state-of-the-art methods used in the field of cancer systems biology. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and practical, Cancer Systems Biology : Methods and Protocols aims to ensure successful results in the further study of this vital field.
The chapters "Identifying Genetic Dependencies in Cancer by Analyzing siRNA Screens in Tumor Cell Line Panels", "Perseus: A Bioinformatics Platform for Integrative Analysis of Proteomics Data in Cancer Research" and "Phosphoproteomics-based Profiling of Kinase Activities in Cancer Cells" are available open access under a CC BY 4.0 license via link.springer.com.
Editors and affiliations
- DOI https://doi.org/10.1007/978-1-4939-7493-1
- Copyright Information Springer Science+Business Media LLC 2018
- Publisher Name Humana Press, New York, NY
- eBook Packages Springer Protocols
- Print ISBN 978-1-4939-7492-4
- Online ISBN 978-1-4939-7493-1
- Series Print ISSN 1064-3745
- Series Online ISSN 1940-6029
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