Bacteriophage Therapy

From Lab to Clinical Practice

  • Joana Azeredo
  • Sanna Sillankorva

Part of the Methods in Molecular Biology book series (MIMB, volume 1693)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Isolation of Bacteriophages

    1. Front Matter
      Pages 1-1
    2. Shigenobu Matsuzaki, Jumpei Uchiyama, Iyo Takemura-Uchiyama, Takako Ujihara, Masanori Daibata
      Pages 3-10
    3. Cristina García-Aljaro, Maite Muniesa, Juan Jofre
      Pages 11-22
  3. Characterization of Bacteriophages

    1. Front Matter
      Pages 31-31
    2. Igor Tolstoy, Andrew M. Kropinski, J. Rodney Brister
      Pages 57-71
  4. Bacteriophage Selection and Cocktail Formulation

    1. Front Matter
      Pages 73-73
    2. Andrey V. Letarov, Eugene E. Kulikov
      Pages 75-84
    3. Maia Merabishvili, Jean-Paul Pirnay, Daniel De Vos
      Pages 99-110
  5. Biodistribution, Host Interaction and Clinical Application

    1. Front Matter
      Pages 111-111
    2. Zuzanna Kaźmierczak, Krystyna Dąbrowska
      Pages 113-122
    3. Nicolas Dufour, Raphaëlle Delattre, Laurent Debarbieux
      Pages 123-137
    4. Vera V. Morozova, Yulia N. Kozlova, Denis A. Ganichev, Nina V. Tikunova
      Pages 151-158
    5. Randolph Fish, Elizabeth Kutter, Gordon Wheat, Bob Blasdel, Mzia Kutateladze, Sarah Kuhl
      Pages 159-170
  6. Production, Purification and Bacteriophage Storage

    1. Front Matter
      Pages 171-171
    2. Maryam Agboluaje, Dominic Sauvageau
      Pages 173-193
    3. Konrad Krysiak-Baltyn, Gregory J. O. Martin, Sally L. Gras
      Pages 195-218
    4. Małgorzata B. Łobocka, Aleksandra Głowacka, Piotr Golec
      Pages 219-230
  7. Safety and Regulation

    1. Front Matter
      Pages 231-231
    2. Jean-Paul Pirnay, Maia Merabishvili, Hilde Van Raemdonck, Daniel De Vos, Gilbert Verbeken
      Pages 233-252
  8. New Phage Therapy Approaches

    1. Front Matter
      Pages 269-269
    2. Pilar Cortés, Mary Cano-Sarabia, Joan Colom, Jennifer Otero, Daniel Maspoch, Montserrat Llagostera
      Pages 271-283
    3. Ana Rita Costa, Catarina Milho, Joana Azeredo, Diana Priscila Pires
      Pages 285-300
  9. Back Matter
    Pages 301-303

About this book


This volume details the experimental approaches suitable for isolating and characterizing bacteriophages to formulating bacteriophage medicinal products and clinical application. Chapters guide readers through regulatory compliance and safety aspects of bacteriophage therapy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and cutting-edge, Bacteriophage Therapy: From Lab to Clinical Practice aims to ensure successful results in the further study of this vital field. 


Bacteriophages fastidious bacteria anaerobic bacteria biofilm Synthetic biology

Editors and affiliations

  • Joana Azeredo
    • 1
  • Sanna Sillankorva
    • 2
  1. 1.LIBRO-Laboratory of Research in Biofilms Rosário OliveiraCEB – Centre of Biological Engineering, University of MinhoBragaPortugal
  2. 2.CEB – Centre of Biological Engineering, University of MinhoBragaPortugal

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media LLC 2018
  • Publisher Name Humana Press, New York, NY
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-4939-7394-1
  • Online ISBN 978-1-4939-7395-8
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site
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