Alpha-1 Antitrypsin Deficiency

Methods and Protocols

  • Florie Borel
  • Christian  Mueller

Part of the Methods in Molecular Biology book series (MIMB, volume 1639)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Jeffrey H. Teckman, Keith S. Blomenkamp
    Pages 1-8
  3. Michael Kalfopoulos, Kaitlyn Wetmore, Mai K. ElMallah
    Pages 9-19
  4. Leslie J. Donato, Melissa R. Snyder, Dina N. Greene
    Pages 21-32
  5. Dina N. Greene, M. C. Elliott-Jelf, David G. Grenache
    Pages 33-44
  6. Irene Belmonte, Luciana Montoto, Francisco Rodríguez-Frías
    Pages 45-60
  7. Béla Suki, Erzsébet Bartolák-Suki, Patricia R. M. Rocco
    Pages 67-75
  8. Stuart Milstein, Kun Qian, Linying Zhang, Alfica Sehgal
    Pages 115-126
  9. Dongtao A. Fu, Martha Campbell-Thompson
    Pages 139-143
  10. Dongtao A. Fu, Martha Campbell-Thompson
    Pages 145-149
  11. Marcela Aparicio-Vergara, Michaela Tencerova, Cecilia Morgantini, Emelie Barreby, Myriam Aouadi
    Pages 161-171
  12. Angelia D. Lockett
    Pages 173-184
  13. Beena Krishnan, Lizbeth Hedstrom, Daniel N. Hebert, Lila M. Gierasch, Anne Gershenson
    Pages 195-209
  14. Qiushi Tang, Alisha M. Gruntman, Terence R. Flotte
    Pages 211-216
  15. Andrew Cox, Christian Mueller
    Pages 217-222
  16. Florie Borel, Qiushi Tang, Christian Mueller
    Pages 223-226
  17. Sarah V. Faull, Anwen E. Brown, Imran Haq, James A. Irving
    Pages 235-248
  18. Michael Campos, Jorge Lascano
    Pages 249-262
  19. Alisha M. Gruntman, Terence R. Flotte
    Pages 267-275
  20. Back Matter
    Pages 277-278

About this book


This volume provides protocols that expand on the latest alpha-1 antitrypsin (AAT) research. The chapters in this book are divided in to three sections: Part I is dedicated to patient-oriented research; part II discusses animal models; and Part III focuses on in vitro studies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Cutting-edge and authoritative, Alpha-1 Antitrypsin Deficiency: Methods and Protocols is a valuable resource for researchers, students, and clinican-scientists interested in AAT deficiency, as well as anyone working in the fields of pulmonology and hepatology.


AAT research pulmonology hepatology animal models therapeutics

Editors and affiliations

  • Florie Borel
    • 1
  • Christian  Mueller
    • 2
  1. 1.Horae Gene Therapy CenterUniversity of Massachusetts Medical SchoolWorcesterUSA
  2. 2.Horae Gene Therapy CenterUniversity of Massachusetts Medical SchoolWorcesterUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media LLC 2017
  • Publisher Name Humana Press, New York, NY
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-4939-7161-9
  • Online ISBN 978-1-4939-7163-3
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site
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