Imaging Mass Spectrometry

Methods and Protocols

  • Laura M. Cole

Part of the Methods in Molecular Biology book series (MIMB, volume 1618)

Table of contents

  1. Front Matter
    Pages i-x
  2. David M. G. Anderson, Wendi Lambert, David J. Calkins, Zsolt Ablonczy, Rosalie K. Crouch, Richard M. Caprioli et al.
    Pages 15-27
  3. Philippa J. Hart, Malcolm R. Clench
    Pages 29-36
  4. Niccolò Mosele, Andrew Smith, Manuel Galli, Fabio Pagni, Fulvio Magni
    Pages 37-47
  5. Maxence Wisztorski, Jusal Quanico, Julien Franck, Benoit Fatou, Michel Salzet, Isabelle Fournier
    Pages 49-63
  6. Emmanuelle Claude, Emrys A. Jones, Steven D. Pringle
    Pages 65-75
  7. Andrew Smith, Manuel Galli, Vincenzo L’Imperio, Fabio Pagni, Fulvio Magni
    Pages 85-94
  8. Arul N. Selvan, Laura M. Cole, Lynne Spackman, Sarah Naylor, Chris Wright
    Pages 95-123
  9. Bryn Flinders, Eva Cuypers, Tiffany Porta, Emmanuel Varesio, Gérard Hopfgartner, Ron M. A. Heeren
    Pages 137-147
  10. Anne Lisa Bruinen, Gregory L. Fisher, Ron M. A. Heeren
    Pages 165-173
  11. Back Matter
    Pages 203-204

About this book


This volume addresses the various techniques and novel applications of mass spectrometry imaging (MSI) and its role as a discovery tool in the field of proteomics, lipidomics, and metabolomics. The chapters in this book demonstrate how MSI can be applied to many areas of research such as clinical pathology, translational medicine, toxicology, biomarkers and response studies, and potential incorporation of MSI into forensic workflows. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Innovative and comprehensive, Imaging Mass Spectrometry: Methods and Protocols is a valuable resource for research scientists and clinicians who are interested in further studies of MSI technologies.


lipidomics Metabolites peptides Hierarchical cluster analysis cell imaging

Editors and affiliations

  • Laura M. Cole
    • 1
  1. 1.The Center for Mass Spectrometry Imaging Biomolecular Science Research CenterSheffield Hallam UniversitySheffieldUnited Kingdom

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media LLC 2017
  • Publisher Name Humana Press, New York, NY
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-4939-7050-6
  • Online ISBN 978-1-4939-7051-3
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site
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