Multiplex Biomarker Techniques

Methods and Applications

  • Paul C. Guest

Part of the Methods in Molecular Biology book series (MIMB, volume 1546)

Table of contents

  1. Front Matter
    Pages i-xv
  2. Reviews

    1. Front Matter
      Pages 1-1
    2. Johann Steiner, Paul C. Guest, Hassan Rahmoune, Daniel Martins-de-Souza
      Pages 19-35
    3. Susan E. Ozanne, Hassan Rahmoune, Paul C. Guest
      Pages 37-55
    4. Gustavo Henrique Martins Ferreira Souza, Paul C. Guest, Daniel Martins-de-Souza
      Pages 57-73
  3. Statistical Considerations

  4. Protocols

    1. Front Matter
      Pages 123-123
    2. Steve F. C. Hawkins, Paul C. Guest
      Pages 125-133
    3. Steve F. C. Hawkins, Paul C. Guest
      Pages 135-142
    4. Steve F. C. Hawkins, Paul C. Guest
      Pages 143-148
    5. Daniella E. Duque-Guimarães, Juliana de Almeida-Faria, Thomas Prates Ong, Susan E. Ozanne
      Pages 149-159
    6. Paul C. Guest, Hassan Rahmoune
      Pages 161-168
    7. Laurie Stephen
      Pages 169-176
    8. Sheila Garcia, Paulo A. Baldasso, Paul C. Guest, Daniel Martins-de-Souza
      Pages 195-204
    9. Adriano Aquino, Paul C. Guest, Daniel Martins-de-Souza
      Pages 205-212
    10. Giuseppina Maccarrone, Juan Jose Bonfiglio, Susana Silberstein, Christoph W. Turck, Daniel Martins-de-Souza
      Pages 223-234
    11. Giuseppina Maccarrone, Alon Chen, Michaela D. Filiou
      Pages 235-243
    12. Erika Velásquez Núñez, Gilberto Barbosa Domont, Fábio César Sousa Nogueira
      Pages 267-274
    13. João G. M. Pontes, Antonio J. M. Brasil, Guilherme C. F. Cruz, Rafael N. de Souza, Ljubica Tasic
      Pages 275-282
    14. Harald Peter, Julia Wienke, Frank F. Bier
      Pages 283-294
    15. Juan L. Martinez-Hurtado, Ali K. Yetisen, Seok-Hyun Yun
      Pages 295-302
  5. Future Directions

  6. Back Matter
    Pages 317-317

About this book


This detailed book arrives as there is an increasing need for multiplex biomarker readouts for improved clinical management and to support the development of new drugs by pharmaceutical companies, due to continuous technical developments and new insights into the high complexity of many diseases. Chapters explore the basic technology platforms being applied in the fields of genomics, proteomics, transcriptomics, metabolomics, and imaging, which are currently the methods of choice in multiplex biomarker research. The book also describes the chief medical areas in which the greatest progress has been made and highlight areas where further resources are required. Written for the highly successful Methods in Molecular Biology series, methodology chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. <
Authoritative and invaluable, Multiplex Biomarker Techniques: Methods and Applications serves as an ideal resource for a wide variety of researchers interested in these vital multiplex techniques.


Drug development Multiplex platforms Personalized medicine Pharmaceuticals Biomarker readouts Transcriptomics Disease classification

Editors and affiliations

  • Paul C. Guest
    • 1
  1. 1.Laboratory of NeuroproteomicsUniversity of Campinas (UNICAMP)CampinasBrazil

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media LLC 2017
  • Publisher Name Humana Press, New York, NY
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-4939-6729-2
  • Online ISBN 978-1-4939-6730-8
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site
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