© 2016

Molecular Pathology in Cancer Research

  • Sunil R. Lakhani
  • Stephen B. Fox
  • Discusses the germline and somatic mutations that are present in different cancers

  • Provides new insights on the abnormalities of structure and function of tumors at the cellular, tissue and organ level

  • Examines the refinement of current classifications of different tumors and the identification of novel predictive and prognostic biomarkers


Table of contents

  1. Front Matter
    Pages i-viii
  2. Lisa Devereux, Heather Thorne, Stephen B. Fox
    Pages 27-49
  3. Chiyan Lau
    Pages 51-66
  4. Chiyan Lau
    Pages 67-82
  5. Sally M. Hunter, Amy E. McCart Reed, Ian G. Campbell, Kylie L. Gorringe
    Pages 83-106
  6. Zhi Ling Teo, Peter Savas, Sherene Loi
    Pages 107-136
  7. Peter Savas, Zhi Ling Teo, Sherene Loi
    Pages 137-149
  8. Marjan E. Askarian-Amiri, Darren J. Korbie, Debina Sarkar, Graeme Finlay
    Pages 151-175
  9. Keerthana Krishnan, Nicole Cloonan
    Pages 177-217
  10. Keith Ashman, Greg Rice, Murray Mitchell
    Pages 219-237
  11. Keith Ashman, Murray Mitchell, Gregory Rice
    Pages 239-260
  12. David Wu, Brent L. Wood, Jonathan R. Fromm
    Pages 279-316
  13. Anthony T. Papenfuss, Daniel Cameron, Jan Schroeder, Ismael Vergara
    Pages 317-333
  14. Deborah Smith, Amy McCart Reed, Sunil R. Lakhani
    Pages 335-348
  15. John S. Mattick
    Pages 349-357
  16. Back Matter
    Pages 359-369

About this book


The aim of the book is to discuss the application of molecular pathology in cancer research, and its contribution in the classification of different tumors and identification of potential molecular targets, as well as how this knowledge may be translated into clinical practice, and the huge impact this field is likely to have in the next 5 to 10 years.


Cancer Molecular Pathology Translational Technology

Editors and affiliations

  • Sunil R. Lakhani
    • 1
  • Stephen B. Fox
    • 2
  1. 1.UQ Centre for Clinical ResearchThe Royal Brisbane and Women’s Hospital, University of Queensland and Pathology QueenslandBrisbaneAustralia
  2. 2.Peter MacCallum Cancer CentreUniversity of MelbourneMelbourneAustralia

About the editors

Sunil Lakhani is State Director, Anatomical Pathology, Pathology Queensland, Professor and Head, Molecular & Cellular Pathology, The School of Medicine, and Head of the Breast Group, The University of Queensland Centre for Clinical Research (UQCCR). His research team comprises scientists and practicing clinicians ensuring a translational focus to the research portfolio. His current research interests include lobular carcinoma and its variants, tumours with a basal phenotype and mechanisms of brain and distant metastases. He is a series editor for the WHO Tumour Classification Books and volume editor for the WHO Classification Tumours of the Breast (4th Ed 2012).

Stephen Fox is Director of Pathology at the Peter MacCallum Cancer Centre, Professorial Fellow at the University of Melbourne and an NH&MRC Practitioner Fellow. His research has primarily been aimed at understanding the molecular basis of cancer, with emphasis on prognosis and predictive markers of human tumours with more recent work focusing on developing and implementing clinical grade diagnostics, particularly in sequencing to match the new paradigm of personalised medicine.

Bibliographic information

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