Hepatocyte Transplantation

Methods and Protocols

  • Peggy Stock
  • Bruno Christ

Part of the Methods in Molecular Biology book series (MIMB, volume 1506)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Introduction

    1. Front Matter
      Pages 1-1
    2. Eugenia Pareja, María José Gómez-Lechón, Laia Tolosa
      Pages 17-42
  3. Experimental Hepatocyte Transplantation

    1. Front Matter
      Pages 43-43
    2. Lander Foquet, Elizabeth M. Wilson, Lieven Verhoye, Markus Grompe, Geert Leroux-Roels, John Bial et al.
      Pages 117-130
    3. Zsuzsanna Polgar, Yanfeng Li, Xia Li Wang, Chandan Guha, Namita Roy-Chowdhury, Jayanta Roy-Chowdhury
      Pages 131-147
    4. Eiji Kobayashi, Shin Enosawa, Hiroshi Nagashima
      Pages 149-160
    5. Nathanael Raschzok, Ulf Teichgräber, Johann Pratschke, Igor M. Sauer
      Pages 201-214
  4. Clinical Hepatocyte Transplantation

    1. Front Matter
      Pages 229-229
    2. Serene M. L. Lee, Tobias S. Schiergens, Maresa Demmel, Reinhard M. K. Thasler, Wolfgang E. Thasler
      Pages 247-258
    3. Raphael P. H. Meier, Elisa Montanari, Philippe Morel, Joël Pimenta, Henk-Jan Schuurman, Christine Wandrey et al.
      Pages 259-271
    4. Ragai R. Mitry, Suttiruk Jitraruch, Valeria Iansante, Anil Dhawan
      Pages 273-281
    5. Giada Pietrosi, Cinzia Chinnici
      Pages 283-294
    6. Louise Coppin, Etienne Sokal, Xavier Stephenne
      Pages 295-315
  5. Computing in Hepatocyte Transplantation

    1. Front Matter
      Pages 317-317
    2. Stefan Hoehme, Adrian Friebel, Seddik Hammad, Dirk Drasdo, Jan G. Hengstler
      Pages 319-362
  6. Back Matter
    Pages 363-365

About this book


This volume features up-to-date protocols for the isolation, preservation, and validation of various cell sources comprising large and small animal models, examining the impact of cell transplantation on acute and chronic liver diseases. Hepatocyte Transplantation: Methods and Protocols guides readers through laboratory protocols for the generation of humanized livers for the assessment of biological actions in vivo and techniques to monitor cell engraftment after cell transplantation in vivo are described and procedures for computational analyses of hepatocyte transplantation. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Comprehensive and practical, Hepatocyte Transplantation: Methods and Protocols is an essential resource for researchers and clinicians to assess the biological as well as the therapeutic potential of hepatocyte transplantation.


cell transplantation chronic liver diseases cell engraftment cell transplantation in vivo liver cell therapy

Editors and affiliations

  • Peggy Stock
    • 1
  • Bruno Christ
    • 2
  1. 1.Department of SurgeryUniversity of LeipzigLeipzigGermany
  2. 2.Department of SurgeryUniversity of LeipzigLeipzigGermany

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media New York 2017
  • Publisher Name Humana Press, New York, NY
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-4939-6504-5
  • Online ISBN 978-1-4939-6506-9
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site
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