The Nuclear Receptor Superfamily

Methods and Protocols

  • Iain J. McEwan, PhD

Part of the Methods in Molecular Biology book series (MIMB, volume 1443)

Table of contents

  1. Front Matter
    Pages i-x
  2. Introduction

    1. Front Matter
      Pages 1-1
  3. Nuclear Receptor Agonists and Antagonists

    1. Front Matter
      Pages 11-11
    2. Jean-Marc A. Lobaccaro, Claude Beaudoin, Bagora Bayala, Silvère Baron, Amalia Trousson
      Pages 13-19
    3. Kara A. DeSantis, Jeffrey L. Reinking
      Pages 21-30
    4. Kush Dalal, Ravi Munuganti, Hélène Morin, Nada Lallous, Paul S. Rennie, Artem Cherkasov
      Pages 31-54
  4. Nuclear Receptor Signalling

  5. Model Systems

    1. Front Matter
      Pages 179-179
    2. Fiona M. Frame, Davide Pellacani, Anne T. Collins, Norman J. Maitland
      Pages 181-201
    3. D. Alwyn Dart, Charlotte L. Bevan
      Pages 203-217
  6. Back Matter
    Pages 249-250

About this book


This volume aims to describe a complementary range of molecular, cell biological, and in vivo protocols used to investigate the structure–function of nuclear receptors, together with experimental approaches that may lead to new drugs to selectively target nuclear receptor-associated diseases. The Nuclear Receptor Superfamily, Second Edition will benefit those starting out in the nuclear receptor research field as well as to more established researchers who wish to apply different methods to a particular receptor or research problem. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and cutting-edge, The Nuclear Receptor Superfamily, Second Edition aims to ensure successful results in the further study of this vital field.


in vivo protocols nuclear receptors target nuclear receptor-associated diseases structure–function of nuclear receptors proteins cell biological

Editors and affiliations

  • Iain J. McEwan, PhD
    • 1
  1. 1.Ins. of Med. Sci. Uni. of AberdeenSch. of Medicine Med. Sci. and NutritionAberdeenUnited Kingdom

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media New York 2016
  • Publisher Name Humana Press, New York, NY
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-4939-3722-6
  • Online ISBN 978-1-4939-3724-0
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site
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