© 2016

Apoptosis Methods in Toxicology

  • Perpetua M.¬†Muganda

Part of the Methods in Pharmacology and Toxicology book series (MIPT)

Table of contents

  1. Front Matter
    Pages i-x
  2. William P. Bozza, Julianne D. Twomey, Su-Ryun Kim, Baolin Zhang
    Pages 13-29
  3. Jack Coleman, Rui Liu, Kathy Wang, Arun Kumar
    Pages 77-92
  4. Akamu J. Ewunkem, Carl D. Parson II, Perpetua M. Muganda, Robert H. Newman
    Pages 93-108
  5. Christian T. Hellwig, Agnieszka H. Ludwig-Galezowska, Markus Rehm
    Pages 109-130
  6. Krupa Ann Mathew, Deepa Indira, Jeena Joseph, Prakash Rajappan Pillai, Indu Ramachandran, Shankara Narayanan Varadarajan et al.
    Pages 131-161
  7. Matthew P. Stokes, Hongbo Gu, Jeffrey C. Silva
    Pages 163-178
  8. Wen Lin Seng, Dawei Zhang, Patricia McGrath
    Pages 193-209
  9. Lan Zhang, Yaxin Zheng, Mao Tian, Shouyue Zhang, Bo Liu, Jinhui Wang
    Pages 211-230
  10. Magisetty Obulesu, Magisetty Jhansilakshmi
    Pages 231-237
  11. Back Matter
    Pages 239-244

About this book


This detailed volume provides a single, valuable reference source for methods that definitively identify and accurately quantify apoptosis. The book begins with common methods utilized to detect and quantitate apoptosis, as well as apoptosis signaling pathways in toxicological and other related research. It continues with multi-parametric and phased apoptosis assays for detecting early and late apoptosis or distinguishing apoptosis from necrosis and autophagy. Subsequent chapters focus on recent advances in real time and high-throughput assays that detect and quantitate apoptosis and apoptosis signaling pathways. Final chapters focus on recent developments in preclinical anticancer therapeutics targeting apoptosis. Written for the Methods in Pharmacology and Toxicology series, chapters feature step-by-step descriptions of the methodologies, as well as expert tips and implementation advice.

Vital and authoritative, Apoptosis Methods in Toxicology serves novice scientists as well as experts, utilizing a range of instruments from common laboratory equipment to high-end expensive and automated machinery capable of performing real time apoptotic measurements.


Programmed cell death Toxicological stresses Dis-regulated apoptosis Apoptotic methods Signaling pathways Preclinical anticancer therapeutics

Editors and affiliations

  • Perpetua M.¬†Muganda
    • 1
  1. 1.Department of BiologyNorth Carolina A&T State UniversityGreensboroUSA

Bibliographic information

  • Book Title Apoptosis Methods in Toxicology
  • Editors Perpetua M. Muganda
  • Series Title Methods in Pharmacology and Toxicology
  • Series Abbreviated Title Meth.Pharmacology,Toxicology
  • DOI
  • Copyright Information Springer Science+Business Media New York 2016
  • Publisher Name Humana Press, New York, NY
  • eBook Packages Springer Protocols
  • Hardcover ISBN 978-1-4939-3586-4
  • Softcover ISBN 978-1-4939-8086-4
  • eBook ISBN 978-1-4939-3588-8
  • Series ISSN 1557-2153
  • Series E-ISSN 1940-6053
  • Edition Number 1
  • Number of Pages X, 244
  • Number of Illustrations 11 b/w illustrations, 35 illustrations in colour
  • Topics Pharmacology/Toxicology
    Cell Cycle Analysis
  • Buy this book on publisher's site
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