NLR Proteins

Methods and Protocols

  • Francesco Di Virgilio
  • Pablo Pelegrín

Part of the Methods in Molecular Biology book series (MIMB, volume 1417)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Natalia Muñoz-Wolf, Ed C. Lavelle
    Pages 1-43
  3. Ann M. Janowski, Fayyaz S. Sutterwala
    Pages 45-62
  4. Nicolas Riteau, Aurélie Gombault, Isabelle Couillin
    Pages 63-74
  5. Catherine Diamond, James Bagnall, David G. Spiller, Michael R. White, Alessandra Mortellaro, Pawel Paszek et al.
    Pages 75-88
  6. Eva Bartok, Maria Kampes, Veit Hornung
    Pages 97-113
  7. Francesco Di Virgilio, Paolo Pinton, Simonetta Falzoni
    Pages 115-129
  8. Sonal Khare, Alexander D. Radian, Andrea Dorfleutner, Christian Stehlik
    Pages 131-143
  9. Michael Beilharz, Dominic De Nardo, Eicke Latz, Bernardo S. Franklin
    Pages 145-158
  10. Fátima Martín-Sánchez, Vincent Compan, Pablo Pelegrín
    Pages 159-168
  11. Yung-Hsuan Wu, Ming-Zong Lai
    Pages 185-195
  12. Baptiste Guey, Virginie Petrilli
    Pages 197-206
  13. Yvan Jamilloux, Fabio Martinon
    Pages 207-215
  14. Vincent Compan, Gloria López-Castejón
    Pages 217-221
  15. Pablo Palazón-Riquelme, Gloria López-Castejón
    Pages 223-229
  16. Valentina Sica, Gwenola Manic, Guido Kroemer, Ilio Vitale, Lorenzo Galluzzi
    Pages 231-245
  17. Sonia Carta, Marco Gattorno, Anna Rubartelli
    Pages 247-254
  18. Michael Beilharz, Dominic De Nardo, Eicke Latz, Bernardo S. Franklin
    Pages E1-E1
  19. Back Matter
    Pages 255-256

About this book


This volume provides a sound basis for the molecular investigation of NLR function in health and disease. Chapters focus on of innate immune receptors, “atypical” inflammasomes, biochemical and novel bioluminescence techniques for the measurement of IL-1b, bioluminescent probe, biochemical and microscopy techniques, techniques to measure caspase-1 activation, cell free systems for the study of inflammasome function, and inflammasome activation. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.


Authoritative and cutting-edge, NLR Proteins: Methods and Protocols aims to ensure successful results in the further study of this vital field.


molecular investigation NLR function technical weaponry biochemical investigation immune receptors measurement of IL-1 extracellular ATP

Editors and affiliations

  • Francesco Di Virgilio
    • 1
  • Pablo Pelegrín
    • 2
  1. 1.Department of Morphology Surgery and Experimental MedicineUniversity of FerraraFerraraItaly
  2. 2.Muricia Biomedical Research Institute (IMIB-Arrixaca), Hospital Virgen de la Arrixaca MurciaMolecular Inflammation GroupMurciaSpain

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media New York 2016
  • Publisher Name Humana Press, New York, NY
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-4939-3564-2
  • Online ISBN 978-1-4939-3566-6
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site
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