Endocannabinoid Signaling

Methods and Protocols

  • Mauro Maccarrone

Part of the Methods in Molecular Biology book series (MIMB, volume 1412)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Natalia Battista, Manuel Sergi
    Pages 19-26
  3. Renger F. Witkamp, Michiel G. J. Balvers
    Pages 27-40
  4. Valeria M. Catani, Valeria Gasperi
    Pages 41-55
  5. Maria Grazia Cascio, Pietro Marini, Roger G. Pertwee
    Pages 57-63
  6. Aniello Schiano Moriello, Luciano De Petrocellis
    Pages 65-76
  7. Sharon Anavi-Goffer, Ruth A. Ross
    Pages 77-83
  8. Pietro Marini, Maria Grazia Cascio, Roger G. Pertwee
    Pages 85-93
  9. Marina Gabaglio, Pamela Prini, Erica Zamberletti, Tiziana Rubino, Daniela Parolaro
    Pages 95-101
  10. Marjolein Soethoudt, Noortje van Gils, Mario van der Stelt, Laura H. Heitman
    Pages 103-111
  11. Toru Uyama, Natsuo Ueda
    Pages 113-122
  12. Filomena Fezza, Nicolina Mastrangelo, Mauro Maccarrone
    Pages 123-130
  13. Monica Bari, Monica Feole, Mauro Maccarrone
    Pages 131-136
  14. Kazuhito Tsuboi, Natsuo Ueda
    Pages 137-148
  15. Tiziana Bisogno
    Pages 149-156
  16. Kwang-Mook Jung, Daniele Piomelli
    Pages 157-168
  17. Juha R. Savinainen, Dina Navia-Paldanius, Jarmo T. Laitinen
    Pages 169-178
  18. Juha R. Savinainen, Dina Navia-Paldanius, Jarmo T. Laitinen
    Pages 179-189
  19. Mark Rau, Simon Nicolussi, Andrea Chicca, Jürg Gertsch
    Pages 191-203
  20. Shalley N. Kudalkar, Philip J. Kingsley, Lawrence J. Marnett
    Pages 205-215
  21. Guus van Zadelhoff, Mario van der Stelt
    Pages 217-225
  22. Natasha T. Snider, Vyvyca J. Walker, Paul F. Hollenberg
    Pages 227-236
  23. Mariangela Pucci, Claudio D’Addario
    Pages 237-246
  24. Jim Wager-Miller, Ken Mackie
    Pages 247-254
  25. Clotilde B. Angelucci, Annalaura Sabatucci, Enrico Dainese
    Pages 267-276
  26. Sergio Oddi, Antonio Totaro, Mauro Maccarrone
    Pages 277-282
  27. Back Matter
    Pages 283-285

About this book


This volume encompasses all major methodologies to interrogate endocannabinoid systems (ECS) and endocannabinoids (eCBs) signaling. With increasing interest towards the manifold activities of eCBs, this book discusses the chemical, biochemical, and molecular biological assays, and activity of distinct elements of the ECS. These include membrane, nuclear receptors, biosynthetic and hydrolytic enzymes, and membrane transporters and oxidative enzymes. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Timely and cutting edge, Endocannabinoid Signaling: Methods and Protocols is a valuable resource and will help chemists, drug designers, biochemists, molecular biologists, cell biologists, pharmacologists, and (electro) physiologists navigate the mare magnum of endocannabinoid research.


Cannabis sativa endocannabinoid system N-arachidonoylethanolamine 2-arachidonoylglycerol membrane and nuclear receptors biosynthetic and hydrolytic enzymes membrane transporters oxidative enzymes drug design pharmacology

Editors and affiliations

  • Mauro Maccarrone
    • 1
  1. 1.Campus Bio-Medico University of RomeDepartment of MedicineRomeItaly

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media New York 2016
  • Publisher Name Humana Press, New York, NY
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-4939-3537-6
  • Online ISBN 978-1-4939-3539-0
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site
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