Cancer Drug Resistance

Overviews and Methods

  • Jose Rueff
  • António Sebastião Rodrigues

Part of the Methods in Molecular Biology book series (MIMB, volume 1395)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. José Rueff, António Sebastião Rodrigues
    Pages 1-18
  3. Pasarat Khongkow, Anna W. Middleton, Jocelyn P.-M. Wong, Navrohit K. Kandola, Mesayamas Kongsema, Gabriela Nestal de Moraes et al.
    Pages 39-53
  4. Romi Ghose, Pankajini Mallick, Guncha Taneja, Chun Chu, Bhagavatula Moorthy
    Pages 55-68
  5. Ramya Krishna Vadlapatla, Dhananjay Pal, Ashim K. Mitra
    Pages 69-74
  6. Marta Gromicho, José Rueff, António Sebastião Rodrigues
    Pages 75-85
  7. Ana Armada, Célia Martins, Gabriella Spengler, Joseph Molnar, Leonard Amaral, António Sebastião Rodrigues et al.
    Pages 87-103
  8. Bruno Costa Gomes, José Rueff, António Sebastião Rodrigues
    Pages 137-162
  9. Ingrid Garajová, Tessa Y. S. Le Large, Elisa Giovannetti, Geert Kazemier, Guido Biasco, Godefridus J. Peters
    Pages 163-187
  10. Bruno Costa Gomes, Bruno Santos, José Rueff, António Sebastião Rodrigues
    Pages 189-205
  11. Marjan E. Askarian-Amiri, Euphemia Leung, Graeme Finlay, Bruce C. Baguley
    Pages 207-227
  12. Maria do Rosário André, Ana Pedro, David Lyden
    Pages 229-239
  13. Vukosava Milic Torres, Lazar Popovic, Fátima Vaz, Deborah Penque
    Pages 281-298
  14. Ankur Gautam, Kumardeep Chaudhary, Rahul Kumar, Sudheer Gupta, Harinder Singh, Gajendra P. S. Raghava
    Pages 299-312
  15. Pasarat Khongkow, Anna W. Middleton, Jocelyn P.-M. Wong, Navrohit K. Kandola, Mesayamas Kongsema, Gabriela Nestal de Moraes et al.
    Pages E1-E1
  16. Back Matter
    Pages 313-314

About this book


This volume discusses the latest advancements and technologies used in cancer drug resistance research. Cancer Drug Resistance: Overviews and Methods contains chapters that cover topics such as: studying the mechanics of resistance to DNA damaging therapeutic drugs; studies to delineate the role of efflux transporters; expression of drug transporters; resistance to targeted therapies in breast cancer; the role of microRNAs in current pancreatic cancer treatment; and cancer exosomes as mediators of drug resistance or clinical and molecular methods in drug development and the use of bioinformatics in the management of cancer drug resistance data. Written in the highly successful Methods in Molecular Biology series format, chapters include overviews of the main issues in cancer drug resistance and the respective mechanisms, as well as introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and practical, Cancer Drug Resistance: Overviews and Methods, is a valuable resource to researchers, oncobiologists and clinical oncologists or anyone else who is interested in the study of cancer and its drug resistances.


cellular resistance multi-drug resistance (MDR) DNA chemotherapy adenosine5'-triphosphate (ATP) binding cassette (ABC) transporters microRNAs proteomics

Editors and affiliations

  • Jose Rueff
    • 1
  • António Sebastião Rodrigues
    • 2
  1. 1.New University of LisbonLisbonPortugal
  2. 2.New University of LisbonLisbonPortugal

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media New York 2016
  • Publisher Name Humana Press, New York, NY
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-4939-3345-7
  • Online ISBN 978-1-4939-3347-1
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site
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