Regenerative Medicine for Degenerative Muscle Diseases

  • Martin K. Childers

Part of the Stem Cell Biology and Regenerative Medicine book series (STEMCELL)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Martin K. Childers, Zejing Wang
    Pages 1-20
  3. Laura L. Smith, Vandana A. Gupta, Alan H. Beggs
    Pages 39-83
  4. Berkcan Akpinar, Elizabeth C. Stahl, Aiping Lu, Johnny Huard
    Pages 85-108
  5. Khalid Medani, Jonathan Riley, Jason Lamanna, Nicholas Boulis
    Pages 109-127
  6. Zoe E. Davidson, Greg Rodden, Davi A. G. Mázala, Cynthia Moore, Carol Papillon, Angela J. Hasemann et al.
    Pages 225-279
  7. Elizabeth U. Parker, Lisa Maves
    Pages 281-293
  8. Diem-Hang Nguyen-Tran, Hannele Ruohola-Baker
    Pages 295-307
  9. Joe N. Kornegay, Martin K. Childers
    Pages 309-329
  10. Back Matter
    Pages 331-336

About this book


This book compiles and explores cutting-edge research in degenerative skeletal disorders, such as Duchenne muscular dystrophy and congenital myopathy, and new stem-cell based therapies and gene replacement therapy. Twelve expertly-authored chapters navigate the nuances of these treatments in an array of contexts and biological systems. The topics covered include: How are urine cells from a patient with Duchenne muscular dystrophy transformed into beating heart cells? What can reprogrammed cells tell us about heart muscle failure? What do gene mutations mean for those born with a muscle disease? How are manufacturing methods applied to human stem cells? Does therapeutic exercise benefit those patients who receive engineered limb muscle? Is there practical advice about nutrition to enhance muscle function for the Duchenne patient? Can microRNAs be useful to regenerate diseased muscle?

 Regenerative Medicine for Degenerative Muscle Diseases is ideal for scientists and clinicians from varying disciplines in genetics, cell biology, virology, cell-based manufacturing, rehabilitation medicine, nutrition, veterinary medicine and neurosurgery. The reader will see how transformative changes occur in medicine that can powerfully impact the future for patients suffering from inherited disorders affecting muscles of the body, including the heart.


Cellular therapeutics Muscle disease and disorder Regenerative medicine Skeletal muscle Stem cell-based therapies

Editors and affiliations

  • Martin K. Childers
    • 1
  1. 1.Department of Rehabilitation MedicineUniversity of Washington Department of Rehabilitation MedicineWINSTON SALEMUSA

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