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Longevity Genes

A Blueprint for Aging

  • GilĀ Atzmon, PhD

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 847)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Diddahally R. Govindaraju
    Pages 1-44
  3. Yair Argon, Tali Gidalevitz
    Pages 45-72
  4. Nuria Martinez-Lopez, Diana Athonvarangkul, Rajat Singh
    Pages 73-87
  5. Linda Broer, Cornelia M. van Duijn
    Pages 107-125
  6. Erik B. van den Akker, Joris Deelen, P. Eline Slagboom, Marian Beekman
    Pages 127-139
  7. David Karasik, Anne Newman
    Pages 141-161
  8. Kendra Bolt, Aviv Bergman
    Pages 163-178
  9. Dan Ben-Avraham
    Pages 179-191
  10. Back Matter
    Pages 193-194

About this book

Introduction

The release of the complete version of the human genome sequence in 2003 has paved the way for defining gene function and genetic background for phenotypic variation in humans and allowed us to study the aging process in a new light. This new volume results from that research and focuses on the genetic and epigenetic process of aging. While the interpretation of the genome data is still in its initial stages, this new volume looks at the evolving understanding of molecular mechanisms involved in cellular processes, gene function associated with complex traits, epigenetic components involve in gene control and the creation of hypothesis-free genome-wide approaches. Longevity Genes: A Blueprint for Aging explores the genetic and genomic elements that can maintain a long life such as DNA damage mechanisms, epigenetics and the way we can use this knowledge to generate customized treatments. It touches on some of the multidisciplinary approaches as well as genomic-wide association technology used to analyze complex traits. This book describes the hunt for genes affecting complex traits using a high throughput technology, with adequate consideration for the selection of an appropriate population, applications of statistical genetics and computational biology, and most importantly, considering phenotype-genotype association studies. Longevity Genes provides coverage of not only established aspects of genetics and aging, but also new approaches and perceptions in this important area of research.

Keywords

aging complex traits genes genomics phenotype

Editors and affiliations

  • GilĀ Atzmon, PhD
    • 1
  1. 1.Albert Einstein College of MedicineBronxUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4939-2404-2
  • Copyright Information Springer Science+Business Media New York 2015
  • Publisher Name Springer, New York, NY
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-1-4939-2403-5
  • Online ISBN 978-1-4939-2404-2
  • Series Print ISSN 0065-2598
  • Series Online ISSN 2214-8019
  • Buy this book on publisher's site
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