Organism Models of Autism Spectrum Disorders

  • Pierre L. Roubertoux

Part of the Neuromethods book series (NM, volume 100)

Table of contents

  1. Front Matter
    Pages i-xviii
  2. Organism Models of Autism Spectrum Disorders: Selecting the Good Species

    1. Front Matter
      Pages 1-1
    2. Nicolas Lévy, Pierre L. Roubertoux
      Pages 3-27
    3. Catherine Bartoli, Arnaud Blanchard, Christine Buske, Gwenaelle Collod-Béroud, Laurent Fasano, Christophe Scajola et al.
      Pages 67-97
    4. Christopher J. Howe, Jaco Serfontein, R. Ellen R. Nisbet, Petrus J. de Vries
      Pages 99-115
  3. Modeling Autism Spectrum Disorder at the Brain Level

    1. Front Matter
      Pages 117-117
    2. Nathalie Baril, Muriel Roth, Rym Djouri
      Pages 119-156
    3. Manuel Ruiz-Rubio, Fernando Calahorro, M. Mar Gámez-del-Estal
      Pages 157-182
    4. Natacha Broucqsault, Cherif Badja, Marie-Cécile Gaillard, Frédérique Magdinier
      Pages 183-215
  4. Communication and Social Interactions

    1. Front Matter
      Pages 263-263
    2. Gene S. Fisch
      Pages 265-282
  5. Mouse Models of Autism Spectrum Disorders as Defined by DSM-5R

    1. Front Matter
      Pages 317-317
    2. Pierre L. Roubertoux
      Pages 319-333
    3. Pierre L. Roubertoux, Michèle Carlier, Sylvie Tordjman
      Pages 335-370
    4. Pierre L. Roubertoux, Catherine Bartoli
      Pages 371-395
  6. Modeling Diseases with a High Prevalence of Autism Spectrum Disorders

  7. Back Matter
    Pages 479-487

About this book


As autism is associated with many rare diseases, this extensive bench book examines how no one single model can be used; multiple organism models are needed, each one corresponding to one of the diseases or to one aspect of a disease. Split into five sections, Organism Models of Autism Spectrum Disorders explores selecting the good species for the specific disease, modeling autism spectrum disorders (ASD) at the brain level, studying communication and social interactions, using vertebrates or invertebrate models of ASD as defined by DSM-5R, as well as pursuing models of diseases associated with an increased incidence of ASDs. Written for the respected Neuromethods series, this detailed volume contains the kind of insight and useful, practical advice that ensures more successful results in the lab.

Comprehensive and handy, Organism Models of Autism Spectrum Disorders will benefit psychiatrists and geneticists, as well as behavioral researchers who, realizing how important it is to improve their knowledge through more molecular approaches, are looking for the most suitable organisms.


Autism Spectrum Disorder (ASD) Molecular approaches Mouse models Social interactions Zebrafish

Editors and affiliations

  • Pierre L. Roubertoux
    • 1
  1. 1.Inserm GMGF UMR_S 910, Génomique Fonctionnelle INSERM UMR_S 910Aix Marseille Université, Génétique MédicaleMarseilleFrance

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media New York 2015
  • Publisher Name Humana Press, New York, NY
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-4939-2249-9
  • Online ISBN 978-1-4939-2250-5
  • Series Print ISSN 0893-2336
  • Series Online ISSN 1940-6045
  • Buy this book on publisher's site
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