Extracellular Matrix

  • Jennie B. Leach
  • Elizabeth M. Powell

Part of the Neuromethods book series (NM, volume 93)

Table of contents

  1. Front Matter
    Pages i-xii
  2. Native Tissue

  3. In Vitro Models

    1. Front Matter
      Pages 33-33
    2. Rolicia F. Martin, Elizabeth M. Powell
      Pages 35-43
    3. Rebecca Conrad, Alice Klausmeyer, Teresa Tsai, Andreas Faissner, Stefan Wiese
      Pages 67-78
    4. Swarnalatha Balasubramanian, Elizabeth M. Powell, Jennie B. Leach
      Pages 91-99
    5. Swarnalatha Balasubramanian, Elizabeth M. Powell, Jennie B. Leach
      Pages 101-109
  4. Injury, Degeneration, and Regeneration

    1. Front Matter
      Pages 111-111
    2. Jianli Hu, Gabrielle M. Curinga, George M. Smith
      Pages 139-149
  5. Therapeutics and Engineered Systems

    1. Front Matter
      Pages 161-161
    2. Caroline P. Addington, Christine Pauken, Sarah E. Stabenfeldt
      Pages 163-179
    3. Jonathan M. Zuidema, María C. Hyzinski-García, Alexander A. Mongin, Ryan J. Gilbert
      Pages 181-195
  6. Back Matter
    Pages 227-229

About this book


This volume provides comprehensive procedures for analyzing the extracellular matrix in native, injured, and engineered neural tissues. Divided into four parts, each focusing on different aspects of the extracellular matrix and the nervous system, Extracellular Matrix covers methods to analyze native tissue, in vitro models for investigating cell-extracellular matrix interactions in a variety of contexts, protocols to investigate the role of the extracellular matrix in nervous system injury, degeneration, and regeneration, as well as therapeutics and engineered systems. Each chapter is written by leading experts and presents established protocols in a concise format, encompassing current technologies as well as methods developed over years of research. Beginning with an introduction to the method, chapters continue with a listing of the materials and equipment, step-by-step protocols, and a Notes section with troubleshooting tips, supplemental details and alternative approaches, as well as a list of references for further information.

As part of the practical and convenient Neuromethods series, Extracellular Matrix serves as an invaluable aid for researchers studying this vital area of neuroscience.


Bioengineering Cell-extracellular matrix interactions Degeneration and regeneration Glycosylation In vitro models Native tissue Nervous system injury Neural tissues Therapeutics

Editors and affiliations

  • Jennie B. Leach
    • 1
  • Elizabeth M. Powell
    • 2
  1. 1.University of Maryland, Baltimore CountyBaltimoreUSA
  2. 2.Department of Anatomy & NeurobiologyUniversity of Maryland School of MedicineBaltimoreUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media New York 2015
  • Publisher Name Humana Press, New York, NY
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-4939-2082-2
  • Online ISBN 978-1-4939-2083-9
  • Series Print ISSN 0893-2336
  • Series Online ISSN 1940-6045
  • Buy this book on publisher's site
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