Cervical Cancer

Methods and Protocols

  • Daniel Keppler
  • Athena W. Lin

Part of the Methods in Molecular Biology book series (MIMB, volume 1249)

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Approaches to the Detection and Analysis of HPV Types

  3. Molecular Pathogenesis of CxCA

    1. Front Matter
      Pages 37-37
    2. Eric J. Ryndock, Jennifer Biryukov, Craig Meyers
      Pages 39-52
    3. Sarah A. Brendle, Neil D. Christensen
      Pages 53-66
    4. Hsu-Kun Wang, Thomas R. Broker, Louise T. Chow
      Pages 93-109
    5. Crystal M. Diep, Gagandeep Kaur, Daniel Keppler, Athena W. Lin
      Pages 121-131
  4. Immune Responses to HPV Infections

    1. Front Matter
      Pages 133-133
    2. Andrew W. Woodham, Adam B. Raff, Diane M. Da Silva, W. Martin Kast
      Pages 135-149
  5. Identification of Novel Potential Drug Targets

    1. Front Matter
      Pages 151-151
    2. Oscar Peralta-Zaragoza, Faustino De-la-O-Gómez, Jessica Deas, Gloria Fernández-Tilapa, Geny del Socorro Fierros-Zárate, Claudia Gómez-Cerón et al.
      Pages 153-171
    3. Wenyi Gu, Nigel McMillan, Chengzhong Yu
      Pages 173-182
    4. Gina J. Ferris, Lauren B. Shunkwiler, Charles A. Kunos
      Pages 183-191
  6. Approaches to Detecting, Typing, and Staging of CxCA

    1. Front Matter
      Pages 201-201
    2. Terry K. Morgan, Michelle Berlin
      Pages 203-212
    3. Julia Dolores Toscano-Garibay, María Luisa Benítez-Hess, Luis Marat Alvarez-Salas
      Pages 221-239
    4. Cara M. Martin, Katharine Astbury, Louise Kehoe, Jacqueline Barry O’Crowley, Sharon O’Toole, John J. O’Leary
      Pages 241-251
  7. Genomic Analyses of CxCA

    1. Front Matter
      Pages 265-265
    2. Mina Kalantari, Hans-Ulrich Bernard
      Pages 267-280
    3. Yaw-Wen Hsu, Rui-Lan Huang, Hung-Cheng Lai
      Pages 281-290
    4. Elva I. Cortés-Gutiérrez, Jose Luis Fernández, Martha I. Dávila-Rodríguez, Carmen López-Fernández, Jaime Gosálvez
      Pages 291-301
  8. Cellular Assays and Cell Culture Models of CxCA

    1. Front Matter
      Pages 303-303
    2. David Gagnon, Amélie Fradet-Turcotte, Jacques Archambault
      Pages 305-316
    3. Jennifer Biryukov, Linda Cruz, Eric J. Ryndock, Craig Meyers
      Pages 317-331
    4. Lisa Yan, Andrew W. Woodham, Diane M. Da Silva, W. Martin Kast
      Pages 333-350
    5. Mayil Vahanan Bose, Thangarajan Rajkumar
      Pages 351-362
  9. Animal Models of CxCA and Experimental Therapeutic Strategies

    1. Front Matter
      Pages 363-363
    2. Nicolas Çuburu, Rebecca J. Cerio, Cynthia D. Thompson, Patricia M. Day
      Pages 365-379
    3. Naz Chaudary, Karolina Jaluba, Melania Pintilie, Richard P. Hill
      Pages 381-391
  10. Back Matter
    Pages 407-413

About this book


Representing the most relevant procedures and technologies aiding the advance of the field of HPV-mediated carcinogenesis of the cervix and other anatomical regions of squamocolumnar transition, such as the anorectum, penis, and oropharynx, Cervical Cancer: Methods and Protocols compiles a detailed collection of practical chapters. The first half of the book covers HPV types, pathogenesis of cervical cancer (CxCA), prevention, and novel potential drug targets, while the second half explores pathology, genomics, modeling of CxCA, and experimental therapeutic strategies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and vital, Cervical Cancer: Methods and Protocols serves as a valuable resource to both bench scientists and clinicians who step into the realm of high-risk HPVs and CxCA for the first time or those who wish to learn novel approaches or expand their toolbox for the study of CxCA.


Cervix CxCA Drug targets Experimental therapeutics Genomic analysis Histopathological detection Human papillomavirus (HPV) Molecular pathogenesis

Editors and affiliations

  • Daniel Keppler
    • 1
  • Athena W. Lin
    • 2
  1. 1.Touro University CaliforniaVallejoUSA
  2. 2.Touro University CaliforniaVallejoUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media New York 2015
  • Publisher Name Humana Press, New York, NY
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-4939-2012-9
  • Online ISBN 978-1-4939-2013-6
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals
Oncology & Hematology
Consumer Packaged Goods