© 2015

Diagnosing Non-small Cell Carcinoma in Small Biopsy and Cytology

  • Andre Luis Moreira
  • Anjali Saqi


  • Provides an up-to-date practical and comprehensive guide

  • Written multidisciplinary experts who are regularly involved in the care of lung cancer patients

  • Richly illustrated with tables, algorithms, and numerous color images


Table of contents

About this book


This volume provides a practical yet comprehensive guide to manage the shift in the diagnosis of lung cancer from large resections to small samples, including cytology specimens and core biopsies. Specifically, it outlines various available minimally-invasive modalities and presents algorithms to optimize and maximize sample collection and processing beginning at the time of tissue acquisition during the procedure.  Secondly, the book provides an overview of the various existing and emerging lung cancer therapies and why a specific diagnosis is crucial.  Key elements for the classification of small biopsies and cytology proposed by the ATS, IASLC, and ERS are highlighted. A section dedicated to immunohistochemistry offers a logical, step-by-step guide to sub-classify lung cancers and to differentiate them from metastases. The text also provides a review of the various molecular tests (and alternatives in cases of scant tissue) required for lung adenocarcinomas. Finally, potential pitfalls to avoid during acquisition, processing, and classification are discussed.

With contributions from  a team of multidisciplinary authors who are regularly involved in the care of lung cancer patients , Diagnosing Non-small Cell Carcinoma in Small Biopsy and Cytology is an invaluable reference guide for pathologists, pathologists-in-training, and allied professionals, including oncologists, pulmonologists, surgeons, and radiologists. ​


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Editors and affiliations

  • Andre Luis Moreira
    • 1
  • Anjali Saqi
    • 2
  1. 1.Department of PathologyMemorial Sloan Kettering Cancer CenterNew YorkUSA
  2. 2.Department of Pathology and Cell BiologyColumbia University Medical Center, New York-Presbyterian HospitalNew YorkUSA

About the editors

Andre Luis Moreira, MD, PhD
Memorial Sloan Kettering Cancer Center, Department of Pathology, New York, New York, USA

Anjali Saqi, MD, MBA
Columbia University Medical Center, Department of Pathology and Cell Biology, New York-Presbyterian Hospital, New York, New York, USA

Bibliographic information

  • Book Title Diagnosing Non-small Cell Carcinoma in Small Biopsy and Cytology
  • Editors Andre Luis Moreira
    Anjali Saqi
  • DOI
  • Copyright Information Springer Science+Business Media New York 2015
  • Publisher Name Springer, New York, NY
  • eBook Packages Medicine Medicine (R0)
  • Hardcover ISBN 978-1-4939-1606-1
  • Softcover ISBN 978-1-4939-5551-0
  • eBook ISBN 978-1-4939-1607-8
  • Edition Number 1
  • Number of Pages X, 229
  • Number of Illustrations 1 b/w illustrations, 80 illustrations in colour
  • Topics Pathology
    Pneumology/Respiratory System
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals


“An excellent and user-friendly guide that encourages a comprehensive approach to NSCLC in small biopsies and cytology specimens. … While this text may be most useful to fellows and cytopathologists who are looking for a practical guide for daily use, the succinct nature of the text and quality of the writing also make it an excellent resource for residents, cytotechnology students, and cytotechnologists who wish to increase their knowledge of how to approach small lung biopsies.” (Marina Vivero, The ASC Bulletin, Vol. LII (6), November, 2015)