Mouse Genetics

Methods and Protocols

  • Shree Ram Singh
  • Vincenzo Coppola

Part of the Methods in Molecular Biology book series (MIMB, volume 1194)

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Mouse Genetics Techniques

    1. Front Matter
      Pages 1-1
    2. Kazuhito Sakamoto, Channabasavaiah B. Gurumurthy, Kay-Uwe Wagner
      Pages 21-35
    3. Petra Kraus, V. Sivakamasundari, Xing Xing, Thomas Lufkin
      Pages 37-62
    4. Susanne Feil, Jana Krauss, Martin Thunemann, Robert Feil
      Pages 113-139
    5. Pedro N. Moreira, Lluís Montoliu
      Pages 141-156
    6. Claudia Piovan, Foued Amari, Francesca Lovat, Qun Chen, Vincenzo Coppola
      Pages 203-224
    7. Olga Simmons, Esther M. Bolanis, Jian Wang, Simon J. Conway
      Pages 225-244
  3. Mouse Genetics in Stem Cells

    1. Front Matter
      Pages 245-245
    2. Kanika Jain, Paul J. Verma, Jun Liu
      Pages 247-252
    3. Pollyanna Agnes Goh, Paul J. Verma
      Pages 253-270
    4. Michael D. Williams, Wilson Wong, Amanda Rixon, Sarang N. Satoor, Anandwardhan A. Hardikar, Mugdha V. Joglekar
      Pages 271-288
    5. Andrei M. Vacaru, Joseph Vitale, Johnathan Nieves, Margaret H. Baron
      Pages 289-312
    6. Lalit Sehgal, Abul Usmani, Sorab N. Dalal, Subeer S. Majumdar
      Pages 327-337
  4. Mouse Genetics in Modeling Human Disease

    1. Front Matter
      Pages 339-339
    2. Vishalakshi Chavali, Shyam Sundar Nandi, Shree Ram Singh, Paras Kumar Mishra
      Pages 385-400
    3. Julia Lorenz, Susanne Grässel
      Pages 401-419
    4. Ganesan Ramesh, Punithavathi Ranganathan
      Pages 421-436
    5. Santhakumar Manicassamy, Indumathi Manoharan
      Pages 437-448
    6. Sarang N. Satoor, Deepak P. Patil, Holly D. Kristensen, Mugdha V. Joglekar, Yogesh Shouche, Anandwardhan A. Hardikar
      Pages 449-469
  5. Back Matter
    Pages 471-475

About this book


Mouse Genetics: Methods and Protocols provides selected mouse genetic techniques and their application in modeling varieties of human diseases. The chapters are mainly focused on the generation of different transgenic mice to accomplish the manipulation of genes of interest, tracing cell lineages, and modeling human diseases. Composed in the highly successful Methods in Molecular Biology series format, each chapter contains a brief introduction, a list of necessary materials, systematic, readily reproducible methods, and a notes section, which shares tips on troubleshooting in order to avoid known pitfalls.


Comprehensive and authoritative, Mouse Genetics: Methods and Protocols promises to deliver fundamental techniques and protocols to geneticists, molecular biologists, cell and developmental biologists, students, and postdoctoral fellows working in the various disciplines of mouse biology and modeling human disease.


Cell lineage tracing Genes of interest Human disease modeling Mouse genome Stem cells Transgenic mice

Editors and affiliations

  • Shree Ram Singh
    • 1
  • Vincenzo Coppola
    • 2
  1. 1.Stem Cell Regulation and Animal Aging Section, Basic Research Laboratory,National Cancer Institute, National Institutes of HealthFrederickUSA
  2. 2.Genetically Engineered Mouse Modeling Core/Department of Molecular Virology, Immunology and Medical Genetics, Wexner Medical Center, Comprehensive Cancer CenterThe Ohio State UniversityColumbusUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media New York 2014
  • Publisher Name Humana Press, New York, NY
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-4939-1214-8
  • Online ISBN 978-1-4939-1215-5
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site
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