© 2014

Regenerative Biology of the Eye

  • Alice Pébay
  • Explores current knowledge on stem cell application for vision loss

  • Showcases different types of stem cells (adult, embryonic, iPSCs) for diseases of the front and back of the eye

  • Highlights data obtained in various models from fish to human, as well as from the bionic eye project for vision regeneration


Part of the Stem Cell Biology and Regenerative Medicine book series (STEMCELL)

Table of contents

  1. Front Matter
    Pages i-xii
  2. Jeremy Ng, Peter D. Currie, Patricia R. Jusuf
    Pages 49-82
  3. Magdalena Hidalgo, Morgane Locker, Albert Chesneau, Muriel Perron
    Pages 83-99
  4. Gary S. L. Peh, Raymond C. B. Wong
    Pages 101-119
  5. Alessia Tassoni, Keith R. Martin
    Pages 121-143
  6. Alex W. Hewitt, Kathryn C. Davidson
    Pages 145-159
  7. Marius Ader, Volker Enzmann, Mike Francke
    Pages 161-175
  8. Patricia Murphy, Michael D. O’Connor
    Pages 177-201
  9. Hongmin Yun, Joel S. Schuman, Yiqin Du
    Pages 203-214
  10. Samuel McLenachan, Dan Zhang, Fred K. Chen
    Pages 215-239
  11. Silmara de Lima, Yoshiki Koriyama, Takuji Kurimoto, Larry I. Benowitz
    Pages 241-256
  12. Lauren N. Ayton, Robyn H. Guymer, Penelope J. Allen, Chi D. Luu
    Pages 257-273
  13. Ilene K. Sugino, Qian Sun, Noounanong Cheewatrakoolpong, Christopher Malcuit, Marco A. Zarbin
    Pages 275-289
  14. Back Matter
    Pages 305-309

About this book


This volume covers visual regenerative biology from current knowledge through future directions and implications. Fifteen chapters discuss the topic thoroughly, from fundamental aspects of developmental biology of the eye through the potential of stem cells and bionic eyes to improve and restore vision. The book also explores the impact of stem cell treatments and regenerative medicine in society.

The economic and public health burdens of blindness are immense, in addition to the psychological and social implications for patients. While current treatments for blindness are limited, regenerative medicine offers exciting prospects for vision improvement or restoration, instilling hope in patients suffering from vision loss. Authoritative and timely, this book is a key resource for scientists working in this expanding and dynamic field.


bionic eye optic nerve stem cell therapies for the eye vision regeneration

Editors and affiliations

  • Alice Pébay
    • 1
  1. 1.Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, Department of OphthalmologyThe University of MelbourneEast MelbourneAustralia

About the editors

Dr. Alice Pébay, Ph.D., is the principal investigator of the Neuroregeneration Unit at the Centre for Eye Research Australia, and a Senior Research Fellow in the Department of Ophthalmology at the University of Melbourne. She holds a Ph.D. in neuroscience and has extensive expertise in cell biology, having published more than 40 peer reviewed articles and chapters in the field of stem cell biology and lysophospholipid biology. Dr Pébay's current research focuses on the mechanisms that enable human pluripotent stem cells to maintain their pluripotency and allow them to differentiate towards specific retinal lineages. Dr Pébay also has comprehensive experience in neurotrauma research and a strong interest in the cellular mechanisms involved in the genetic disease, Friedreich Ataxia.

Bibliographic information

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