Genomic Applications in Pathology

  • George Jabboure Netto
  • Iris Schrijver

Table of contents

  1. Front Matter
    Pages i-xv
  2. Genomic Technologies

    1. Front Matter
      Pages 1-1
    2. Matthew W. Anderson
      Pages 19-29
    3. Sugganth Daniel, Alberto Paniz-Mondolfi, Federico A. Monzon
      Pages 31-43
    4. Cornelia Braicu, Beatriz M. Maia, Ioana Berindan-Neagoe, George A. Calin
      Pages 45-70
    5. Marija Balic, Richard J. Cote
      Pages 71-84
  3. Practice Related Aspects of Clinical Genomics

    1. Front Matter
      Pages 99-99
    2. Richard L. Haspel
      Pages 101-110
    3. Joshua L. Deignan
      Pages 111-118
    4. Roger D. Klein
      Pages 129-139
    5. Henry T. Greely
      Pages 141-155
  4. Clinical Implementation of Diagnostic Genomics

    1. Front Matter
      Pages 157-157
    2. David K. Crockett, Karl V. Voelkerding
      Pages 177-196
    3. Hao Ho, Christopher D. Gocke
      Pages 197-207
    4. Michael O. Dorschner
      Pages 209-223
    5. Arunkanth Ankala, Madhuri R. Hegde
      Pages 225-240
    6. Tina M. Hambuch, Carri-Lyn Mead
      Pages 241-257
  5. Genomic Applications in Oncology

    1. Front Matter
      Pages 295-295
    2. Kevin E. Fisher, Charles E. Hill
      Pages 297-319
    3. Matija Snuderl
      Pages 321-339
    4. Sun M. Ahn, Nishant Agrawal
      Pages 341-358
    5. Leticia De Mattos-Arruda, Britta Weigelt, Jorge S. Reis-Filho
      Pages 359-382
    6. Reinhard Büttner, Margarete Odenthal, Sabine Merkelbach-Bruse
      Pages 383-413
    7. Andreas Jung, Ralph Hruban
      Pages 415-434
    8. Sarah Chiang, Luciano G. Martelotto, Britta Weigelt
      Pages 465-487
    9. Eva Wardelmann, Wolfgang Hartmann
      Pages 503-532
  6. Genomic Applications of Inherited and Infectious Diseases

    1. Front Matter
      Pages 533-533
    2. Bryan L. Krock, Rong Mao, D. Hunter Best, Elaine Lyon
      Pages 535-551
    3. Rehan Qayyum
      Pages 553-562
    4. Martina I. Lefterova, Niaz Banaei, Benjamin A. Pinsky
      Pages 581-604
  7. Back Matter
    Pages 605-622

About this book


Genomic Applications in Pathology provides a state-of-the art review of the scientific principles underlying next generation genomic technologies and the required bioinformatics approaches to analyses of the daunting amount of data generated by current and emerging genomic technologies. Implementation roadmaps for various clinical assays such as single gene, gene panels, whole exome and whole genome assays are discussed together with issues related to reporting, including the pathologist’s role in interpretation and clinical integration of genomic tests results. Genomic applications for site-specific solid tumors and hematologic neoplasms are detailed, as well as genomic applications in pharmacogenomics, inherited genetic diseases, and infectious diseases. The latest iteration of practice recommendations and guidelines in genomic testing, put forth by stakeholder professional organizations such as the Association for Molecular Pathology  and the College of American Pathologists, are also discussed in the volume, as well as regulatory issues and laboratory accreditation related to genomic testing.

Written by experts in the field, Genomic Applications in Pathology provides a comprehensive resource that is of great value to practicing molecular pathologists, hematopathologists, other subspecialized pathologists, general pathologists, pathology trainees, oncologists, and geneticists.​


Circulating Tumor Cells Clinical Genomics Genomic Medicine Pharmacogenomics RNAseq Sequencing Assays miRNA Assays

Editors and affiliations

  • George Jabboure Netto
    • 1
  • Iris Schrijver
    • 2
  1. 1.Departments of Pathology, Oncology and UrologyJohns Hopkins UniversityBaltimoreUSA
  2. 2.Department of PathologyStanford University School of MedicineStanfordUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media New York 2015
  • Publisher Name Springer, New York, NY
  • eBook Packages Medicine
  • Print ISBN 978-1-4939-0726-7
  • Online ISBN 978-1-4939-0727-4
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals