Translation in Progress

  • Robert C. Roach
  • Peter H. Hackett
  • Peter D. Wagner

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 903)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Epigenetic Alterations in Hypoxia

    1. Front Matter
      Pages 1-1
    2. Claudio Sartori, Stefano F. Rimoldi, Hervé Duplain, Thomas Stuber, Sophie Garcin, Emrush Rexhaj et al.
      Pages 17-28
    3. Claudio Sartori, Stefano F. Rimoldi, Emrush Rexhaj, Yves Allemann, Urs Scherrer
      Pages 55-62
  3. Hypoxia and High Altitude Residents

    1. Front Matter
      Pages 63-63
    2. Stefano F. Rimoldi, Emrush Rexhaj, Mercedes Villena, Carlos Salinas Salmon, Yves Allemann, Urs Scherrer et al.
      Pages 83-100
  4. Hypoxia and the Brain

    1. Front Matter
      Pages 129-129
    2. Craig D. Steinback, Marc J. Poulin
      Pages 131-144
    3. Kyle T. S. Pattinson, Richard G. Wise
      Pages 145-156
    4. Douglas R. Corfield, Leanne C. McKay
      Pages 157-167
    5. Boyan K. Garvalov, Till Acker
      Pages 169-185
    6. Daniel Bulte
      Pages 187-199
    7. Nephtali Marina, Vitaliy Kasymov, Gareth L. Ackland, Sergey Kasparov, Alexander V. Gourine
      Pages 201-207
    8. Grant R. J. Gordon, Clare Howarth, Brian A. MacVicar
      Pages 209-219
  5. Molecular Oxygen Sensing

    1. Front Matter
      Pages 245-245
    2. Christopher W. Pugh
      Pages 259-271
  6. Physiological Responses to Hypoxia

    1. Front Matter
      Pages 273-273
    2. Keith R. Burgess, Philip N. Ainslie
      Pages 275-283
    3. Jon Peter Wehrlin, Bernard Marti, Jostein Hallén
      Pages 357-374
    4. José A. L. Calbet, Carsten Lundby, Robert Boushel
      Pages 395-408
    5. Jeffrey B. Graham, Corey J. Jew, Nicholas C. Wegner
      Pages 409-426
    6. Michael P. W. Grocott, D. Z. H. Levett, D. S. Martin, M. H. Wilson, A. Mackenney, S. Dhillon et al.
      Pages 427-437
    7. John B. West
      Pages 457-463
  7. Back Matter
    Pages 465-772

About this book


The latest in a series of books from the International Hypoxia Symposia, this volume spans reviews on key topics in hypoxia, and abstracts from poster and oral presentations. The biannual International Hypoxia Symposia are dedicated to hosting the best basic scientific and clinical minds to focus on the integrative and translational biology of hypoxia. Long before ‘translational medicine’ was a catchphrase, the founders of the International Hypoxia Symposia brought together basic scientists, clinicians and physiologists to live, eat, ski, innovate and collaborate in the Canadian Rockies.

This collection of reviews and abstracts is divided into six sections, each covering new and important work relevant to a broad range of researchers interested in how humans adjust to hypoxia, whether on the top of Mt. Everest or in the pulmonary or cardiology clinic at low altitude. The sections include:

  • Epigenetic Variations in Hypoxia
  • High Altitude Adaptation
  • Hypoxia and Sleep
  • Hypoxia and the Brain
  • Molecular Oxygen Sensing
  • Physiological Responses to Hypoxia

Dr. Robert Roach is the Director of the Altitude Research Center at the University of Colorado. He specializes in the study of physiological adaptations by humans to high altitude, with a recent emphasis on the genomic responses to allow humans to thrive in hypoxia. 

Dr. Peter Wagner is a Distinguished Professor of Medicine and Bioengineering at the University of California, San Diego. His research addresses the theoretical and experimental basis of oxygen transport and its limitations in the lungs and skeletal muscles in health and disease. 

Dr. Peter Hackett is a world-renowned high altitude expert and altitude research pioneer. He is a leading authority on altitude illness, high altitude climbing, wilderness medicine, and the effects of altitude on people living and working in the mountains.


hypoxia immunology high altitude molecular oxygen sensing sleep physiological response

Editors and affiliations

  • Robert C. Roach
    • 1
  • Peter H. Hackett
    • 2
  • Peter D. Wagner
    • 3
  1. 1.Altitude Research CenterUniversity of Colorado Anschutz MedicalAURORAUSA
  2. 2.Institute for Altitude MedicineTellurideUSA
  3. 3.Division of Physiology 0623AUniversity of California - San DiegoLa JollaUSA

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