Translational Neuroscience

Fundamental Approaches for Neurological Disorders

  • Mark H. Tuszynski

Table of contents

  1. Front Matter
    Pages i-xv
  2. Mark H. Tuszynski
    Pages 1-6
  3. Molecular Approaches

    1. Front Matter
      Pages 7-7
    2. Giridhar Murlidharan, R. Jude Samulski, Aravind Asokan
      Pages 9-32
    3. Mark H. Tuszynski, Alan H. Nagahara
      Pages 33-64
    4. Krystof Bankiewicz, Waldy San Sebastian, Lluis Samaranch, John Forsayeth
      Pages 65-88
    5. Michael G. Kaplitt, Matthew J. During
      Pages 89-98
    6. Wade K. Self, Timothy M. Miller
      Pages 99-109
    7. Dolan Sondhi, Ronald G. Crystal, Stephen M. Kaminsky
      Pages 111-129
    8. Ioana Goganau, Armin Blesch
      Pages 131-153
    9. Thomas J. McCown
      Pages 155-165
    10. Darren Wolfe, David Krisky, James Goss, James Wechuck, Marina Mata, David J. Fink
      Pages 167-183
  4. Cellular Approaches

    1. Front Matter
      Pages 185-185
    2. Andrés M. Bratt-Leal, Jeanne F. Loring
      Pages 187-201
    3. Edsel M. Abud, Mathew Blurton-Jones
      Pages 203-225
    4. Anthony Donsante, Lindsey Nicole Urquia, Nicholas M. Boulis
      Pages 227-258
    5. Pamela Sarkar, Neil Scolding
      Pages 259-273
    6. M. Joana Osorio, Steven A. Goldman
      Pages 275-296
    7. Paul Lu, Ruhel Ahmad, Mark H. Tuszynski
      Pages 297-315
    8. Regina Teresa Martuscello, Brent A. Reynolds, Santosh Kesari
      Pages 335-356
  5. Novel Pharmacological Approaches

    1. Front Matter
      Pages 357-357
    2. Kevin D. Rynearson, Rudolph E. Tanzi, Steven L. Wagner
      Pages 359-368
    3. Anna Magdalena Guzik-Kornacka, Flóra Vajda, Martin E. Schwab
      Pages 369-397
    4. Gerald W. Zamponi, Chongyang Han, Stephen G. Waxman
      Pages 415-436
  6. Activity-Dependent Plasticity and Neurorehabilitation

    1. Front Matter
      Pages 437-437
    2. Lea Awai, Volker Dietz, Armin Curt
      Pages 439-456
    3. Arthur Prochazka
      Pages 457-478
    4. Ausaf A. Bari, Nicolas Kon Kam King, Nir Lipsman, Andres M. Lozano
      Pages 499-516
    5. Patrick D. Lyden, Jessica Lamb, Padmesh S. Rajput
      Pages 517-538
    6. Mark H. Tuszynski
      Pages 581-584

About this book


Translational Neuroscience offers a far-reaching and insightful series of perspectives on the effort to bring potentially revolutionary new classes of therapies to the clinic, thereby transforming the treatment of human nervous system disorders. Great advances in the fields of basic neuroscience, molecular biology, genomics, gene therapy, cell therapy, stem cell biology, information technology, neuro devices, rehabilitation and others over the last 20 years have generated unprecedented opportunities to treat heretofore untreatable disorders of the nervous system. This book provides a wide-ranging yet detailed sample of many of these efforts, together with the methods for pursuing clinical translation and assessing clinical outcomes. Among the topics covered are Alzheimer’s disease, Parkinson’s disease, stroke, multiple sclerosis, epilepsy, motor neuron disease, pain, inborn errors of metabolism, brain tumors, spinal cord injury, neuroprosthetics, rehabilitation and clinical trial design/consideration.

Translational Neuroscience is aimed at basic neuroscientists, translational neuroscientists and clinicians who seek to gain a perspective on the nature and promise of translational therapies in the current era. Both students and established professionals will benefit from the content.


Spinal cord injury Nervous System Brain Neuropsychiatric Disorders Neurotrauma

Editors and affiliations

  • Mark H. Tuszynski
    • 1
  1. 1.UnivofCA-SanDiego,VeteransAdmintnMedCntrTranslational Neuroscience InstituteLa JollaUSA

Bibliographic information

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