Current Topics

  • William L. McGuire

Table of contents

  1. Front Matter
    Pages i-xv
  2. Richard J. Santen, Eugeniusz Samojlik
    Pages 79-115
  3. Gary C. Chamness, William L. McGuire
    Pages 149-197
  4. J. Bailar III
    Pages 227-238
  5. Richard B. Everson, Marc E. Lippman
    Pages 239-267
  6. Back Matter
    Pages 269-271

About this book


Breast cancer continues to be a major problem. In Volume 1 of this series we dealt exclusively with topics concerned with therapy. In Volume 2 we explored various aspects of experimental biology which are critical to our developing better methods of diagnosis and treatment. In the pres­ ent volume, we tum to a series of individual topics of considerable interest, including systemic methods for hormonal ablation, screening for early cancer, male breast cancer, and more. The first chapter addresses the question of why some breast tumors metastasize and others do not. Based on elegant animal tumor models, Kim believes that metastasizing tumor cells are the undesirable by­ product of the host immune surveillance mechanism. Unstable mem­ brane structures lead to shedding of membrane constituents, abnormal locomotive properties, and evasion of the host defense system. Factors which alter membrane structure will therefore have to be considered in our approach to the management of early breast cancer.


breast cancer cancer carcinoma hormones mammography metastasis screening tumor

Editors and affiliations

  • William L. McGuire
    • 1
  1. 1.University of Texas Health Science CenterSan AntonioUSA

Bibliographic information

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Oncology & Hematology