Molecular Biology of Aging

  • Avril D. Woodhead
  • Anthony D. Blackett
  • Alexander Hollaender

Part of the Basic Life Sciences book series (BLSC, volume 35)

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Symposium Lecture - I

  3. Wear and Tear Hypotheses

    1. J. R. Totter
      Pages 13-14
    2. Richard G. Cutler
      Pages 15-73
    3. B. J. Merry, Anne M. Holehan
      Pages 117-141
    4. J. E. Fleming, J. Miquel, K. G. Bensch
      Pages 143-156
  4. Aging in Cellular Proteins

  5. Symposium Lecture - II

    1. Alex Comfort
      Pages 213-229
  6. Changes in DNA with Age - I

    1. D. J. Anderson, A. L. M. Watson, E. J. Yunis
      Pages 231-240
    2. Vincent J. Cristofalo, Paul D. Phillips, Katherine M. Brooks
      Pages 241-253
    3. Samuel Goldstein, Arun Srivastava, Karl T. Riabowol, Robert J. Shmookler Reis
      Pages 255-267
  7. Changes in DNA with Age - II

  8. Symposium Lecture - III

    1. Lewis Thomas
      Pages 361-372
  9. Diseases Featuring Altered Rates of Aging

    1. Leon Sokoloff
      Pages 373-374
    2. W. Ted Brown, Michael Zebrower, Fred J. Kieras
      Pages 375-396
    3. Peter D. Gorevic, Jules Elias, Nancy Peress
      Pages 397-418
    4. Robert W. Gracy, M. L. Chapman, J. K. Cini, M. Jahani, T. O. Tollefsbol, K. Ü. Yüksel
      Pages 427-442
  10. Future Directions in Aging Research

    1. Ronald W. Hart, Angelo Turturro
      Pages 443-445
    2. Leonard Hayflick
      Pages 447-460
    3. J. Edwin Seegmiller
      Pages 461-463
  11. Back Matter
    Pages 465-482

About this book


It is delightful but humbling to find my face at the start of these Proceedings--there are innumerable other faces which could equally weIl stand there, from among the band who have fore­ gathered at every gerontology conference since the subject was launched in its present form; but I deeply appreciate being there. Gerontology d. id not grow by accident. Its present standing is the fruit of careful planning, undertaken by European and American scientists back in the 1950's. In those days it was still a "fringe" science, and the conspirators had much the standing of the 1920's Interplanetary Society. The United States itself is the offspring of conspiracy, for when the results of conspiracy are beneficent, the conspirators become Founding Fathers. This has been the case with gerontology. The present meeting is especially gratifying because the papers have been recitals of normal, hard-science investigation. We had to get through the rigors of a long period of semantic argument and a long period of one-shot general theories before this kind of meeting, normal in all other research fields, could take place. It was also necesssary to breed in the menagerie a generation of excellent investigators aware of the theoretical background but unintimidated by it, who share our conviction that human aging is comprehensible and probably controllable, and who go into the laboratory to attack specifics.


DNA DNA repair aging biology brain cancer development enzymes immunity mitochondria molecular biology planning proliferation protein

Editors and affiliations

  • Avril D. Woodhead
    • 1
  • Anthony D. Blackett
    • 2
  • Alexander Hollaender
    • 3
  1. 1.Brookhaven National LaboratoryUptonUSA
  2. 2.University of Manchester Institute of Science and TechnologyManchesterUK
  3. 3.Council for Research Planning in Biological Sciences, Inc.USA

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