Models for Assessing Drug Absorption and Metabolism

  • Ronald T. Borchardt
  • Philip L. Smith
  • Glynn Wilson

Part of the Pharmaceutical Biotechnology book series (PBIO, volume 8)

Table of contents

  1. Front Matter
    Pages i-xxii
  2. Ismael J. Hidalgo
    Pages 35-50
  3. Robin Griffiths, Ann Lewis, Phillip Jeffrey
    Pages 67-84
  4. Christopher J. H. Porter, William N. Charman
    Pages 85-102
  5. Elizabeth Quadros, James P. Cassidy, Harry Leipold
    Pages 103-113
  6. M. Vore, Y. Liu, T. C. Ganguly
    Pages 115-120
  7. Edward L. LeCluyse, Peter L. Bullock, Andrew Parkinson, Jerome H. Hochman
    Pages 121-159
  8. Kim L. R. Brouwer, Ronald G. Thurman
    Pages 161-192
  9. Marcelo M. Gutierrez, Claire M. Brett, Kathleen M. Giacomini
    Pages 193-210
  10. Noriko Okudaira, Yuichi Sugiyama
    Pages 211-238
  11. Kenneth L. Audus, Lawrence Ng, Wen Wang, Ronald T. Borchardt
    Pages 239-258
  12. Carla B. Washington, Kathleen M. Giacomini, Claire M. Brett
    Pages 259-283
  13. Patricia M. Reardon
    Pages 309-323
  14. Doris Wall, Doreen Pierdomenico
    Pages 347-359
  15. Mohammed Eljamal, Sudha Nagarajan, John S. Patton
    Pages 361-374
  16. Robert L. Bronaugh
    Pages 375-386
  17. Jim E. Riviere
    Pages 387-407
  18. Sy-Juen Wu, Joseph R. Robinson
    Pages 409-424
  19. Vincent H. L. Lee
    Pages 425-436
  20. Back Matter
    Pages 437-444

About this book


Pharmaceutical scientists in industry and academia will appreciate this single reference for its detailed experimental procedures for conducting biopharmaceutical studies. This well-illustrated guide allows them to establish, validate, and implement commonly used in situ and in vitro model systems. Chapters provide ready access to these methodologies for studies of the intestinal, buccal, nasal and respiratory, vaginal, ocular, and dermal epithelium as well as the endothelial and elimination barriers.


absorption drug drugs kidney metabolism pharmaceutical research transport

Editors and affiliations

  • Ronald T. Borchardt
    • 1
  • Philip L. Smith
    • 2
  • Glynn Wilson
    • 3
  1. 1.The University of KansasLawrenceUSA
  2. 2.SmithKline Beecham PharmaceuticalsKing of PrussiaUSA
  3. 3.Tacora CorporationSeattleUSA

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag US 1996
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4899-1865-9
  • Online ISBN 978-1-4899-1863-5
  • Series Print ISSN 1078-0467
  • Buy this book on publisher's site
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