© 1995

Diet and Cancer

Molecular Mechanisms of Interactions

  • American Institute for Cancer Research

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 354)

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Carrie A. Redlich, Ariette M. Van Bennekum, Joel A. Wirth, William S. Blaner, Darryl Carter, Lynn T. Tanoue et al.
    Pages 17-29
  3. Richard L. Eckert, Chapla Agarwal, Joan R. Hembree, Chee K. Choo, Nywana Sizemore, Sheila Andreatta van Leyen et al.
    Pages 31-44
  4. JoEllen Welsh, Maura Simboli-Campbell, Carmen J. Narvaez, Martin Tenniswood
    Pages 45-52
  5. David Feldman, Roman J. Skowronski, Donna M. Peehl
    Pages 53-63
  6. Steven H. Zeisel, Kerry-Ann da Costa, Craig D. Albright, Ok-Ho Shin
    Pages 65-74
  7. Z. Ronai, J. Tillotson, L. Cohen
    Pages 85-95
  8. Nawfal W. Istfan, Jennifer Wan, Zhi-Yi Chen
    Pages 149-156
  9. Andrew Yen, Megan Williams, Joseph D. Platko, Channing Der, Mark Hisaka, Alexander M. Feigin et al.
    Pages 157-218
  10. Back Matter
    Pages 219-222

About this book


The fifth of the annual research conferences of the American Institute for Cancer Research was held September l-2, 1994, at the L'Enfant Plaza Hotel in Washington, DC. Appropriately, in view of current directions in research, the theme was "Diet and Cancer: Molecular Mechanisms of Interactions". This proceedings volume contains chapters from the platform presentations and abstracts from the poster session held on the end of the first day. The subtopics for the tl;rree sessions held were "Retinoids, Vitamins A and Din Cancer Prevention and Therapy," "Choline and Lipids: Signal Transduction, Gene Expression and Growth Regulation," and "Dietary Factors and Regulation of Oncogenes, Growth and Differentiation. " A general overview on vitamins A and D emphasized that A and D, in addition to their established roles in vision, reproduction, and bone mineral homeostasis, may play significant roles in regulating cell function. Vitamin A metabolites, trans-retinoic acid and 9-cis-retinoic acid, regulate growth and differentiation. Furthermore, vitamin A­ deprived animals were more susceptible to both spontaneous and carcinogen-induced tumors. Epidemiological studies showed a correlation between low A intake and higher incidences of certain types of human cancers. Conversely, all-trans retinoic acid is useful in treatment and control of certain types of cancer. Physiologically, Vitamin D is converted to the active form, l ,25-dihydroxyvitamin D (VD). VD regulates hormone production and secretion, myocardial contractility, vascu­ 3 3 3 lar tone, and growth inhibition and differentiation.


Carcinom Colon DNA Interferon Nutrition Translation Vitamin A Vitamin D cancer cancer prevention gene expression

Editors and affiliations

  • American Institute for Cancer Research
    • 1
  1. 1.USA

Bibliographic information

  • Book Title Diet and Cancer
  • Book Subtitle Molecular Mechanisms of Interactions
  • Editors Maryce M. Jacobs
  • Series Title Advances in Experimental Medicine and Biology
  • DOI
  • Copyright Information Springer-Verlag US 1995
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Hardcover ISBN 978-0-306-45067-9
  • Softcover ISBN 978-1-4899-0951-0
  • eBook ISBN 978-1-4899-0949-7
  • Series ISSN 0065-2598
  • Edition Number 1
  • Number of Pages XIV, 222
  • Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
  • Topics Immunology
    Animal Anatomy / Morphology / Histology
    Plant Sciences
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