Reproductive Toxicology

In Vitro Germ Cell Developmental Toxicology, from Science to Social and Industrial Demand

  • Jesús del Mazo

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 444)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Advances in Improving Human Risk Estimation

    1. Wolfgang R. Schäfer, Hans Peter Zahradnik
      Pages 5-8
    2. Ana M. Soto, Cheryl L. Michaelson, Nancy V. Prechtl, Beau C. Weill, Carlos Sonnenschein, Fatima Olea-Serrano et al.
      Pages 9-28
    3. Patricia Pazos, Pilar Pérez, Ana Rivas, Rafael Nieto, Begoña Botella, Jorge Crespo et al.
      Pages 29-40
  3. New Approaches for In Vitro Analysis of Germ Cells Exposure to Toxicological Agents

    1. Minoo Rassoulzadegan, François Cuzin
      Pages 51-57
    2. Ewa Rajpert-De Meyts, Heidrun Lauke, Niels E. Skakkebæk
      Pages 59-66
    3. Nicole Clemann, Rudolf Bechter
      Pages 67-71
    4. Maria Bobadilla, Laura Suter, Rudolf Bechter
      Pages 73-78
    5. Grant Haines, Brian Marples, Paul Daniel, Ian Morris
      Pages 79-93
    6. Mario Altamirano-Lozano, Elia Roldán, Edmundo Bonilla, Miguel Betancourt
      Pages 105-111
    7. Martin Seifert, Stefanie Haindl, Bertold Hock
      Pages 113-117
  4. Molecular and Developmental Approaches for Assessing Reproductive Toxicity:

    1. A. Collick, Philippe Bois, Gemma Grant, Jerome Buard
      Pages 119-127
    2. F. Maranghi, C. Macrì, C. Ricciardi, A. V. Stazi, A. Mantovani
      Pages 129-136
    3. Luis A. López-Fernández, Pascal Lopez, Fréderique Vidal, Fariba Ranc, François Cuzin, Minoo Rassoulzadegan
      Pages 153-162
  5. Animal Risk Assessment. In Vivo / In Vitro Comparative Analysis

    1. Immaculada Ponsa, Laura Tusell, Ricard Álvarez, Anna Genescà, Rosa Miró, Josep Egozcue
      Pages 185-190
    2. Mariana Rojas, Eduardo Bustos-Obregón, Francisco Martínez-García, Héctor Contreras, Javier Regadera
      Pages 201-206
    3. Betting Schrag, Uwe Ensenbach, José Maria Navas, Helmut Segner
      Pages 207-214
  6. Back Matter
    Pages 221-223

About this book


Numerous reports demonstrate that the reproductive system could be affected by multiple potential toxicological agents. The volume includes different aspects of the development of new approaches to in vitro testing using sperm cells and systems involved on reproduction in mammals. Comparative analysis of in vivo and in vitro methods has been included to take steps towards the further development of and applications of new systems for germline toxicology.


Drogen Embryo assessment development production

Editors and affiliations

  • Jesús del Mazo
    • 1
  1. 1.Centro de Investigaciones Biológicas (CISC)MadridSpain

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag US 1998
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4899-0091-3
  • Online ISBN 978-1-4899-0089-0
  • Series Print ISSN 0065-2598
  • Buy this book on publisher's site
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