Dendritic Cells in Fundamental and Clinical Immunology

1. Dendritic Cell Development and Migration

   1. Stimulation of Langerhans Cell Migration in Mice by Tumour Necrosis Factor α and Interleukin 1β

      • M. Cumberbatch, R. J. Dearman, I. Kimber

      Pages 121-124

   2. Langerhans Cells Require Signals from Both Tumour Necrosis Factor α and Interleukin 1β for Migration

      • M. Cumberbatch, R. J. Dearman, I. Kimber

      Pages 125-128

   3. α6 Integrins are Required for Langerhans Cell Migration

      • A. A. Price, M. Cumberbatch, I. Kimber, A. Ager

      Pages 129-132

   4. Functional Expression and Modulation of C5a Receptor (CD88) on Skin Dendritic Cells

      • A. Morelli, A. Larregina, E. Chuluyán, E. Kolkowski, L. Fainboim

      Pages 133-138

   5. Unilineage Dendritic Cell Cultures Generated by Purified Human Hematopoietic Progenitor Cells

      • E. Montesoro, U. Testa, M. Gabbianelli, C. Peschle

      Pages 139-143

   6. CD14 is Expressed by Subsets of Murine Dendritic Cells and Upregulated by Lipopolysaccharide

      • Karsten Mahnke, Eva Becher, Paola Ricciardi-Castagnoli, Thomas A. Luger, Thomas Schwarz, Stephan Grabbe

      Pages 145-159

   7. TGF-β1 Dependent Generation of LAG+ Dendritic Cells from CD34+ Progenitors in Serum-Free Medium

      • Herbert Strobl, Elisabeth Riedl, Clemens Scheinecker, Concha Bello-Fernandez, Winfried F. Pickl, Otto Majdic et al.

      Pages 161-165

2. Antigen Uptake, Processing, and Presentation

   1. A Newly Identified Antigen Retention Compartment in the FSDC Precursor Dendritic Cell Line

      • Manfred B. Lutz, Patrizia Rovere, Monique J. Kleijmeer, Caroline U. Aßmann, Viola M. J. Oorschot, Maria Rescigno et al.

      Pages 167-169

   2. Mannose Receptor Mediated Uptake of Antigens Strongly Enhances HLA-Class II Restricted Antigen Presentation by Cultured Dendritic Cells

      • M. C. Agnes A. Tan, A. Mieke Mommaas, Jan Wouter Drijfhout, Reina Jordens, Jos J. M. Onderwater, Desiree Verwoerd et al.

      Pages 171-174

   3. Mechanisms of FcεRI-IgE-Facilitated Allergen Presentation by Dendritic Cells

      • Dieter Maurer, Christof Ebner, Bärbel Reininger, Peter Petzelbauer, Edda Fiebiger, Georg Stingl

      Pages 175-178

   4. Localization and Intracellular Transport of MHC Class II Molecules in Bone Marrow-Derived Dendritic Cells

      • P. Pierre, S. J. Turley, J. Meltzer, A. Mirza, R. Steinman, I. Mellman

      Pages 179-182

   5. Mannose Receptor Mediated Antigen Uptake and Presentation in Human Dendritic Cells

      • Anneke J. Engering, Marina Cella, Donna M. Fluitsma, Elisabeth C. M. Hoefsmit, Antonio Lanzavecchia, Jean Pieters

      Pages 183-187

   6. Enhanced Antigen Presenting Cell Function Following in Vivo Priming

      • Geneviève De Becker, Philippe Mockel, Jacques Urbain, Oberdan Leo, Muriel Moser

      Pages 189-193

   7. Dendritic Cells from Mice Lacking the Invariant Chain Express High Levels of Membrane MHC Class II Molecules in Vivo

      • Patrizia Rovere, Frédérique Forquet, Valérie S. Zimmermann, Jeannine Trucy, Paola Ricciardi-Castagnoli, Jean Davoust

      Pages 195-201

   8. T Lymphocyte Mediated Regulation of Costimulator Molecule Expression on Human Dendritic Cells

      • A. D. McLellan, R. V. Sorg, D. B. Fearnley, B. D. Hock, R. J. Tiedemann, J. D. Fraser et al.

      Pages 203-206

   9. Activation of Immature Dendritic Cells Via Membrane Sialophorin (CD43)

      • Emanuele Fanales-Belasio, Giovanna Zambruno, Andrea Cavani, Giampiero Girolomoni

      Pages 207-212

   10. Processing of Exogenous Protein Antigen by Murine Dendritic Cells for Presentation to Cytotoxic T Lymphocytes

       • Marloes L. H. De Bruijn, Danita H. Schuurhuis, Hans Vermeulen, Karin A. J. de Cock, Cornelis J. M. Melief

       Pages 213-220

   11. The TH1 Lymphokine Interferon-γ is a Potent Upregulator of Dendritic Cells with Phagocytic Capacity in GM-CSF Supplemented Bone Marrow Cultures

       • Christoph Scheicher, Heike Corban, Vera Hof, Michael Robbers, Konrad Reske

       Pages 221-225

   12. Functional Role of CD101 on Skin Dendritic Cells

       • Martine Bagot, Isabelle Martinel, Dominique Charue, Marie-Laure Boulland, Janine Wechsler, Armand Bensussan et al.

       Pages 227-232

   13. Presentation of Tetanus Toxoid to Autologous T Cells by Dendritic Cells Generated from Human Blood

       • Susanne Büchele, Reinhard Höpfl

       Pages 233-237

These proceedings contain selected contributions from the participants to the Fourth International Symposium on Dendritic cells that was held in Venice (Lido) Italy, from Oc­ tober 5 to 10, 1996. The symposium was attended by more than 500 scientists coming from 24 different countries. Studies on dendritic cells (DC) have been greatly hampered by the difficulties in preparing sufficient cell numbers and in a reasonable pure form. At this meeting it has been shown that large quantities of DC can be generated from precursors in both mice and humans, and this possibility has enormously encouraged studies aimed to characterize DC physiology and DC-specific genes, and to employ DC therapeutically as adjuvants for im­ munization. The possibility of generating large numbers of autologous DC that can be used in the manipulation of the immune response against cancer and infectious diseases has tremendously boosted dendritic cell research and the role of DC in a number of medi­ cal areas has been heatedly discussed.

• Antigen
• HIV
• infections
• infectious disease
• interferon
• physiology

• CNR Center of Cytopharmacology, University of Milan, Milan, Italy

  Paola Ricciardi-Castagnoli

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