Free Radicals, Oxidative Stress, and Antioxidants

Pathological and Physiological Significance

  • Tomris Özben

Part of the NATO ASI Series book series (NSSA, volume 296)

Table of contents

  1. Front Matter
    Pages i-ix
  2. Mechanisms Involved in Free Radical Reactions

    1. Ben-Zhan Zhu, Ronit Har-El, Nahum Kitrossky, Mordechai Chevion
      Pages 15-24
    2. İ. Hamdi Öğüş, Mevhibe Balk, Yasemin Aksoy, Meltem Müftüoğlu, Nazmi Özer
      Pages 25-37
    3. Earl R. Stadtman
      Pages 51-64
    4. Bruce A. Freeman, Jason Eiserich, Valerie O’Donnell
      Pages 65-78
    5. B. Leininger-Muller, C. Jolivalt, R. Herber, P. Bertrand, G. Siest
      Pages 79-84
    6. Wolf Bors, Christa Michel, Werner Heller, Heinrich Sandermann Jr.
      Pages 85-92
    7. Dimitrios Galaris, Stelianos Kokkoris, Ioannis Toumpoulis, Panagiotis Korantzopoulos
      Pages 93-101
    8. W. Sluiter, A. Pietersma, J. F. Koster
      Pages 103-108
  3. Free Radicals in Health and Disease

    1. Ferruccio Guerrieri, Giovanna Pellecchia, Sergio Papa
      Pages 109-119
    2. José Viña, Miguel Asensi, Juan Sastre, José A. Ferrero, Emilio Servera, Amparo Gimeno et al.
      Pages 121-129
    3. Antonella Scavazza, Gabriella Leonarduzzi, Simonetta Camandola, Maurizio Parola, Giuseppe Poli
      Pages 145-149
    4. Fiorella Biasi, Juan Cutrin, Elena Chiarpotto, Mauro Salizzoni, Alessandro Franchello, Fausto Zamboni et al.
      Pages 157-162
    5. Tomris Özben
      Pages 163-187
    6. A. S. Yalçın, Goncagül Haklar, Belgin Küçükkaya, Meral Yüksel, Hale Saybaşılı
      Pages 189-193
    7. E. Berenshtein, E. Banin, N. Kitrossky, M. Chevion, J. Pe’er
      Pages 229-235
  4. Antioxidants

    1. Enrique Cadenas
      Pages 237-251
    2. Mordechai Chevion, Ben-Zhan Zhu, Eduard Berenshtein
      Pages 267-283
    3. Ingrid Emerit, Jany Vassy, Frédéric Garban, Paulo Filipe, Joao Freitas
      Pages 285-291
    4. Patrik Andrée, Gustav Dallner, Lars Ernster
      Pages 293-314
    5. Helmut Sies, Wilhelm Stahl
      Pages 315-322
    6. Nesrin K. Özer, Önder Sirikci, Suzan Taha, N. Kaya Engin, Daniel Boscoboinik, Sophie Clément et al.
      Pages 333-342
  5. Methodology

    1. Wolf Bors, Christa Michel, Kurt Stettmaier
      Pages 363-374
    2. A. Süha Yalçın, Goncagül Haklar, Belgin Küçükkaya, Meral Yüksel, Gönül Dalaman
      Pages 385-390
  6. Back Matter
    Pages 391-395

About this book


There has been an explosion of research related to free radicals and antioxidants in recent years, and hundreds of laboratories worldwide are actively involved in many as­ pects of free radicals, oxidative stress, and antioxidants. The literature on these topics in­ creases exponentially every year. Over the last few years, we have been fortunate to witness a widespread recognition of the important role of free radicals in a wide variety of pathological conditions including diseases such as atherosclerosis, cardiovascular and neurological diseases, ischemia, emphysema, diabetes, radiation injury, cancer, etc. In ad­ dition, many laboratories are studying the role of free radicals in the inexorable process of aging. Increased evidence involves free radicals with the etiology of various diseases, thereby suggesting the use of antioxidants as a viable therapeutic approach for the treat­ ment of free radical mediated pathologies. Despite these impressive developments, many important aspects of free radical and antioxidant research are open for investigation. It is important to understand the overall mechanisms involved in free radical mediated physiological and pathological conditions. This knowledge will undoubtedly lead to the development of new therapeutic approaches to prevent or control free radical related diseases. This book contains the proceedings of the NATO Advanced Study Institute (ASI) on "Free Radicals, Oxidative Stress, and Antioxidants: Pathological and Physiological Sig­ nificance," which was held in Antalya, Turkey from May 24-June 4, 1997.


ATP Oxidation aging antioxidant cancer oxidative stress protein regeneration spectroscopy

Editors and affiliations

  • Tomris Özben
    • 1
  1. 1.Akdeniz UniversityAntalyaTurkey

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