© 1998

Allergy and Allergic Diseases

The New Mechanisms and Therapeutics

  • Judah A. Denburg

Table of contents

  1. Inflammation: Molecular Aspects

    1. Hirokazu Kurata, Ken-ichi Arai
      Pages 331-350
    2. Andrew Wardlaw
      Pages 351-371
    3. David H. Broide
      Pages 373-382
  2. Signaling in Allergic Reactions

    1. Front Matter
      Pages 383-383
    2. Anthony P. Sampson, Martin K. Church
      Pages 385-393
    3. Donald MacGlashan Jr.
      Pages 395-413
    4. Hirohito Kita
      Pages 415-441
  3. Pathogenesis

    1. Front Matter
      Pages 443-443
    2. Niels Mygind, Ronald Dahl
      Pages 445-457
    3. Allen P. Kaplan
      Pages 459-480
    4. Johannes Ring, Ulf Darsow, Dietrich Abeck
      Pages 481-492
    5. Paul M. O’Byrne
      Pages 493-508
    6. Sergio Bonini, Stefano Bonini
      Pages 509-519
  4. Therapeutics

    1. Front Matter
      Pages 521-521
    2. Christopher J. Corrigan
      Pages 523-539
    3. Harold S. Nelson
      Pages 541-557
    4. Alan M. Edwards, Alexis E. Harper, D. Ken Rainey, Alan A. Norris
      Pages 559-566
    5. Peter M. Hockey, Ratko Djukanović, William R. Roche, Steven T. Holgate
      Pages 567-579
  5. Back Matter
    Pages 581-599

About this book


In Allergy and Allergic Diseases: The New Mechanisms and Therapeutics, a distinguished international panel of researchers and clinicians review the latest findings on the cellular and molecular foundations of allergic diseases, particularly those of the airway, skin, and bowel. The key topics treated span the range from epidemiology and the mechanisms of inflammation, to signaling in pathogenesis and allergic reactions. Each contributor treats the pathophysiology of allergy in various organ-based diseases and syndromes, emphasizing important new findings from cellular and molecular biology that illuminate these diseases, but also reveal important leads for the development of novel drugs and therapeutic strategies.

Allergy and Allergic Diseases: The New Mechanisms and Therapeutics highlights the interface between basic and clinical science in allergic disease. Its up-to-date, clinically relevant approach constitutes the new standard knowledge base in clinical immunology and allergy, not only for specialists, but also for internists, for scientists studying the cellular and molecular biology of inflammation and immunity, and for researchers focused on drug discovery and therapeutics. Authoritative and timely, Allergy and Allergic Diseases is clearly the today's indispensable new resource for all physicians and investigators seeking a deeper understanding of allergy in both its basic and clinical aspects.


Immunity inflammatory response molecular biology molecular mechanisms regulation signal transduction

Editors and affiliations

  • Judah A. Denburg
    • 1
  1. 1.Department of MedicineMcMaster UniversityHamiltonCanada

Bibliographic information

  • Book Title Allergy and Allergic Diseases
  • Book Subtitle The New Mechanisms and Therapeutics
  • Editors Judah A. Denburg
  • DOI
  • Copyright Information Humana Press 1998
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Springer Book Archive
  • Hardcover ISBN 978-0-89603-404-4
  • Softcover ISBN 978-1-61737-026-7
  • eBook ISBN 978-1-4757-2776-0
  • Edition Number 1
  • Number of Pages XVI, 599
  • Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
  • Topics Allergology
  • Buy this book on publisher's site


"The book presents a broad overview of the field at a level that is easy to understand. . .provides an advanced understanding of the current state of the field and leaves the reader receptive to new concepts and therapies for allergic disease that will soon be forthcoming"-Dale T. Umetsu, MD, PhD, review in the April 29, 1999 issue of The New England Journal of Medicine

" excellent book on allergy and allergic diseases....a carefully thought-out whole, starting with IgE mechanisms, environmental allergens, and the new "jungle hypothesis" of atopic disorders beginning in early childhood. The book then proceeds to cellular and molecular aspects of inflammation, highlighting the key points of the pathogenesis of allergy in different organs, and ending with the essentials of treatment." - Allergy

"The book certainly has the five main features described in the presentation: it is written by leading authorities in allergy provides an updated comprehensive survey of the mechanisms of allergic diseases; it illustrates the cellular and molecular bases of allergy and asthma; it emphasizes pathogenesis and the relevance of mechanisms to clinical expression; it includes useful information on therapeutics and possibilities for drug discovery." - EACCI