© 1998

Allergy and Allergic Diseases

The New Mechanisms and Therapeutics

  • Judah A. Denburg

Table of contents

  1. Front Matter
    Pages i-xvi
  2. Epidemiology/IgE

    1. Front Matter
      Pages 1-1
    2. Juha Punnonen, Jan E. de Vries
      Pages 13-40
    3. Thomas A. E. Platts-Mills, Judith A. Woodfolk, Lisa M. Wheatley
      Pages 41-60
    4. Bengt Björkstén
      Pages 61-82
  3. Inflammation: Cellular Aspects

    1. Front Matter
      Pages 83-83
    2. Mark D. Inman, Roma Sehmi, Paul M. O’Byrne, Judah A. Denburg
      Pages 85-102
    3. Angus J. MacDonald, Fiona L. Wills, Tong-Jun Lin, A. Dean Befus
      Pages 103-125
    4. Thomas Bieber
      Pages 127-137
    5. Redwan Moqbel, Paige Lacy
      Pages 139-165
    6. Peter Valent
      Pages 167-174
    7. Peter J. Barnes
      Pages 175-194
    8. Sergio Romagnani
      Pages 195-210
    9. Marc Humbert, Stephen R. Durham
      Pages 211-227
    10. Paul A. MacAry, David M. Kemeny
      Pages 229-241
    11. Peter K. Jeffery, Mariusz J. Gizycki, Andrew V. Rogers
      Pages 243-280
    12. Mary H. Perdue, Derek M. McKay
      Pages 281-303
  4. Inflammation: Molecular Aspects

    1. Front Matter
      Pages 305-305
    2. Daniel L. Hamilos
      Pages 307-329

About this book


In Allergy and Allergic Diseases: The New Mechanisms and Therapeutics, a distinguished international panel of researchers and clinicians review the latest findings on the cellular and molecular foundations of allergic diseases, particularly those of the airway, skin, and bowel. The key topics treated span the range from epidemiology and the mechanisms of inflammation, to signaling in pathogenesis and allergic reactions. Each contributor treats the pathophysiology of allergy in various organ-based diseases and syndromes, emphasizing important new findings from cellular and molecular biology that illuminate these diseases, but also reveal important leads for the development of novel drugs and therapeutic strategies.

Allergy and Allergic Diseases: The New Mechanisms and Therapeutics highlights the interface between basic and clinical science in allergic disease. Its up-to-date, clinically relevant approach constitutes the new standard knowledge base in clinical immunology and allergy, not only for specialists, but also for internists, for scientists studying the cellular and molecular biology of inflammation and immunity, and for researchers focused on drug discovery and therapeutics. Authoritative and timely, Allergy and Allergic Diseases is clearly the today's indispensable new resource for all physicians and investigators seeking a deeper understanding of allergy in both its basic and clinical aspects.


Immunity inflammatory response molecular biology molecular mechanisms regulation signal transduction

Editors and affiliations

  • Judah A. Denburg
    • 1
  1. 1.Department of MedicineMcMaster UniversityHamiltonCanada

Bibliographic information

  • Book Title Allergy and Allergic Diseases
  • Book Subtitle The New Mechanisms and Therapeutics
  • Editors Judah A. Denburg
  • DOI
  • Copyright Information Humana Press 1998
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Springer Book Archive
  • Hardcover ISBN 978-0-89603-404-4
  • Softcover ISBN 978-1-61737-026-7
  • eBook ISBN 978-1-4757-2776-0
  • Edition Number 1
  • Number of Pages XVI, 599
  • Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
  • Topics Allergology
  • Buy this book on publisher's site


"The book presents a broad overview of the field at a level that is easy to understand. . .provides an advanced understanding of the current state of the field and leaves the reader receptive to new concepts and therapies for allergic disease that will soon be forthcoming"-Dale T. Umetsu, MD, PhD, review in the April 29, 1999 issue of The New England Journal of Medicine

" excellent book on allergy and allergic diseases....a carefully thought-out whole, starting with IgE mechanisms, environmental allergens, and the new "jungle hypothesis" of atopic disorders beginning in early childhood. The book then proceeds to cellular and molecular aspects of inflammation, highlighting the key points of the pathogenesis of allergy in different organs, and ending with the essentials of treatment." - Allergy

"The book certainly has the five main features described in the presentation: it is written by leading authorities in allergy provides an updated comprehensive survey of the mechanisms of allergic diseases; it illustrates the cellular and molecular bases of allergy and asthma; it emphasizes pathogenesis and the relevance of mechanisms to clinical expression; it includes useful information on therapeutics and possibilities for drug discovery." - EACCI