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Dietary Fat and Cancer

Genetic and Molecular Interactions

  • American Institute for Cancer Research

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 422)

Table of contents

  1. Front Matter
    Pages i-xvi
  2. Laurence N. Kolonel
    Pages 1-19
  3. Steven K. Clinton
    Pages 21-37
  4. Michael C. Archer, Ahmed El-Sohemy, Laurie L. Stephen, Alaa F. Badawi
    Pages 39-46
  5. David P. Rose, Jeanne M. Connolly, Xin-Hua Liu
    Pages 47-55
  6. Robert W. Hardy, Nalinie S. M. D. Wickramasinghe, S. C. Ke, Alan Wells
    Pages 57-69
  7. Keqin Tang, Kenneth V. Honn
    Pages 71-84
  8. Robert S. Chapkin, Yi-Hai Jiang, Laurie A. Davidson, Joanne R. Lupton
    Pages 85-96
  9. Craig D. Albright, Rong Liu, Mai-Heng Mar, Ok-Ho Shin, Angelica S. Vrablic, Rudolf I. Salganik et al.
    Pages 97-107
  10. Daniel J. Noonan, Michelle L. O’Brien
    Pages 127-135
  11. John A. Barnard, J. A. Delzell, N. M. Bulus
    Pages 137-144
  12. David A. Bernlohr, Natalie Ribarik Coe, Melanie A. Simpson, Ann Vogel Hertzel
    Pages 145-156
  13. Gillian M. Small, Igor V. Karpichev, Yi Luo
    Pages 157-166
  14. Donald B. Jump, Steven D. Clarke, Annette Thelen, Marya Liimatta, Bing Ren, Maria V. Badin
    Pages 167-176
  15. Diane F. Birt
    Pages 177-179
  16. American Institute for Cancer Research
    Pages 181-243
  17. Back Matter
    Pages 245-252

About this book

Introduction

The annual research conference for 1996 of the American Institute for Cancer Re­ search was again held at the Loews L'Enfant Plaza Hotel in Washington, DC, August 29 and 30. The topic for this, the seventh in the series, was "Dietary Fat and Cancer: Genetic and Molecular Mechanisms. " Two separate presentations were given as the conference overview. "Fat and Cancer: The Epidemiologic Evidence in Perspective" noted that die­ tary fat can be saturated, largely from animal or dairy sources, or mono- or polyunsatu­ rated, mostly from plant sources. Unlike animal fats, fish contain relatively high levels of protective omega-3 fatty acids. Although the hypothesis that dietary fat is associated with cancer is plausible, the mechanisms involved are reasonable, and many animal studies support the hypothesis, there are many obstacles in any direct extrapolation to humans, in­ cluding imprecise measures of dietary fat intake, variability in individual diets, and spe­ cies variations. Despite these limitations, there is a weak positive correlation between colon cancer and dietary fat intake, but with substantial differences for various ethnic groups. In the case of breast cancer, there is substantial variation among countries and eth­ nic groups, but the overall evidence indicated an association with fat in the diet. Epidemiologic studies of dietary fat and prostate cancer are more consistent and most show a positive relationship. However, it was not clear which types of dietary fat were im­ plicated in the effect.

Keywords

Colon Metabolite apoptosis cancer gene expression genes molecular mechanisms

Editors and affiliations

  • American Institute for Cancer Research
    • 1
  1. 1.USA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4757-2670-1
  • Copyright Information Springer-Verlag US 1997
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4419-3282-2
  • Online ISBN 978-1-4757-2670-1
  • Series Print ISSN 0065-2598
  • Buy this book on publisher's site
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