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© 1995

Observational Studies

Book

Part of the Springer Series in Statistics book series (SSS)

Table of contents

  1. Front Matter
    Pages i-xv
  2. Paul R. Rosenbaum
    Pages 1-12
  3. Paul R. Rosenbaum
    Pages 13-58
  4. Paul R. Rosenbaum
    Pages 59-86
  5. Paul R. Rosenbaum
    Pages 87-135
  6. Paul R. Rosenbaum
    Pages 136-153
  7. Paul R. Rosenbaum
    Pages 154-173
  8. Paul R. Rosenbaum
    Pages 174-186
  9. Paul R. Rosenbaum
    Pages 187-199
  10. Paul R. Rosenbaum
    Pages 200-224
  11. Paul R. Rosenbaum
    Pages 225-227
  12. Back Matter
    Pages 229-231

About this book

Introduction

An observational study is an empirical investigation of the effects of treatments, policies, or exposures. It differes from an experiment in that the investigator cannot control the assignments of treatments to subjects. Scientists across a wide range of disciplines undertake such studies, and the aim of this book is to provide a sound statistical account of the principles and methods for the design and analysis of observational studies. Readers are assumed to have a working knowledge of basic probability and statistics, but otherwise the account is reasonably self-contained. Throughout there are extended discussions of actual observational studies to illustrate the ideas discussed. These are drawn from topics as diverse as smoking and lung cancer, lead in children, nuclear weapons testing, and placement programs for students. As a result, many researchers involved in observational studes will find this an invaluable companion to their work.

Keywords

Analysis Bias Observational Studies Sensitivity Statistica Treatment Effects control design knowledge probability randomized experiment sound statistics testing

Authors and affiliations

  1. 1.Department of StatisticsUniversity of PennsylvaniaPhiladelphiaUSA

Bibliographic information

  • Book Title Observational Studies
  • Authors Paul R. Rosenbaum
  • Series Title Springer Series in Statistics
  • DOI https://doi.org/10.1007/978-1-4757-2443-1
  • Copyright Information Springer-Verlag New York 1995
  • Publisher Name Springer, New York, NY
  • eBook Packages Springer Book Archive
  • Hardcover ISBN 978-0-387-94482-1
  • Softcover ISBN 978-1-4757-2445-5
  • eBook ISBN 978-1-4757-2443-1
  • Series ISSN 0172-7397
  • Edition Number 1
  • Number of Pages XV, 231
  • Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
  • Topics Statistics, general
  • Buy this book on publisher's site
Industry Sectors
Finance, Business & Banking
Pharma

Reviews

From the reviews of the second edition:

TECHNOMETRICS

"This is certainly a book that persons involved with studying the effects of treatments or policies on the affected subjects will want to own. It would seem that persons would want to replace their 1E with this updated and considerably expanded edition."

JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION

"Rosenbaum provides a clear presentation of concepts and language (e.g., overt vs. hidden bias, matching, referent as opposed to control subjects), and presents specific methodological procedures as well as larger philosophical issues…an important book that should be widely read."

D. OAKES, UNIVERSITY OF ROCHESTER, USA

"This is a fascinating book which combines elegant theory with good practical advice on applications, including in-depth discussion of many interesting examples from diverse fields."  

SHORT BOOK REVIEWS

"This second edition is about fifty percent larger than the original. The flavour is the same. The book provides a thoughtful discussion, at a mathematical and conceptual level, of what can and cannot be learned from observational studies."

"There are many new examples and problems which enrich the reading of the book. The structure of having problems and bibliographic notes is very useful. … There is a very thorough study of hidden bias … which makes this book very different from many existing books in epidemiology." (Anup Dewanji, Sankhya, Vol. 65 (3), 2003)

"The book by Paul R. Rosenbaum is devoted to the investigation of such observational studies which explore the effects of exposures, treatments, or policies but which are characterized by the fact that the investigator lacks control of treatment assignment. Rosenbaum gives a concise and mathematically founded approach to a careful interpretation of the findings of observational studies … . The book becomes especially valuable for applied researchers by numerous carefully discussed examples from different fields of application, which supplement the given theoretical arguments … ." (I. Pigeot, Metrika, August, 2003)

"The purpose of this book is to give an account of statistical principles and methods for the design and analysis of observational studies. … I believe this book will be very useful to researchers and graduate students in the biomedical and social sciences. The distinction between randomized experiments and observational studies is of vital importance for the difficult task of providing correct conclusions from observational studies. Without any doubt, I would recommend this new edition be added to our libraries as an interesting reference book." (M. Dolores Ugarte, Journal of Applied Statistics, Vol. 30 (10), 2003)

"The second edition of this remarkable book is about fifty percent larger than the first, published in 1995. … Technical issues are treated thoroughly but do not interfere with conceptual matters. Each chapter concludes with problems both conceptual and technical. The mathematical level is variable. The book would be adequate for a seminar course for students with some previous knowledge of the subject area." (Ricardo Maronna, Statistical Papers, Vol. 45 (1), 2004)

"This second edition of a well-known and useful book has been expanded and revised … . Observational studies, whether retrospective or prospective, represent the majority of research in the medical, social, and environmental sciences and are very different from designed experiments. Rosenbaum provides a clear presentation of concepts and language (e.g., overt vs. hidden bias, matching, referent as opposed to control subjects), and presents specific methodological procedures as well as larger philosophical issues. … Observational Studies is an important book that should be widely read." (Peter C. Wollan, JASA, December, 2004)

"Here is a book in which the author has made a considerable effort in producing a second edition (2E) for a specialized book. He has turned a slender little book … into a substantial and comprehensive text. … This is certainly a book that persons involved with studying the effects of treatments or policies on the affected subjects will want to own. It would seem that persons would want to replace their 1E with this updated and considerably expanded edition." (Technometrics, Vol. 45 (2), May, 2003)

"An observational study is an empirical investigation of the effects caused by a treatment, policy, or intervention, in which it is not possible to assign subjects at random to treatments or controls, as would be done in controlled experiments. … This book is extremely useful to researchers and graduate students in the biomedical and social sciences." (T. Postelnicu, Zentralblatt MATH, Vol. 985, 2002)