© 1985

Comparison of Type I and Type II Diabetes

Similarities and Dissimilarities in Etiology, Pathogenesis, and Complications

  • Mladen Vranic
  • Charles H. Hollenberg
  • George Steiner

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 189)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Introduction

  3. Is the Present Classification Valid And Sufficient

  4. Genetics and Immunology

    1. M. Alan Permutt, Teresa Andreone, John Chirgwin, Steve Elbein, Peter Rotwein, Matthew Orland
      Pages 89-106
    2. Ake Lernmark, Steinunn Baekkeskov, Ivan Gerling, William Kastern, Caj Knutson, Birgitte Michelsen
      Pages 107-127
  5. Pathophysiology and Metabolic Abnormalities

    1. W. Kenneth Ward, James C. Beard, Jeffrey B. Halter, Daniel Porte Jr.
      Pages 137-158
    2. Barry I. Posner, Masood N. Kahn, John J. M. Bergeron
      Pages 159-173
    3. Jerrold M. Olefsky, Robert R. Revers, Mel Prince, Robert R. Henry, William T. Garvey, John A. Scarlett et al.
      Pages 175-205
    4. J. Dupre, A. Baer, M. Lee, T. J. McDonald, J. Radziuk, N. W. Rodger et al.
      Pages 207-225
    5. Mladen Vranic, Alexandre Wajngot, Suad Efendic
      Pages 227-245
  6. Complications

    1. S. Michael Mauer, Blanche M. Chavers
      Pages 299-303
    2. Peter James Dyck, Anthony Windebank, Hitoshi Yasuda, F. John Service, Robert Rizza, Bruce Zimmerman
      Pages 305-320
    3. Ronald Klein, Matthew D. Davis, Scot E. Moss, Barbara E. K. Klein, David L. DeMets
      Pages 321-335
  7. Conclusions

    1. George F. Cahill Jr.
      Pages 337-342

About this book


Five years ago, a new system of classification of the various types of diabetes was proposed. This publication provides an inte­ grated picture of the latest information on the similarities and dissimilarites of two types of diabetes. It contains contributions from morphologists, physiologists, biochemists, immunologists, pathologists, geneticists, clinicians and epidemiologists. In the first section, the basis for the present classification and its limitations are discussed. In addition, there is a discussion of gestational diabetes and heterogeneity of some sub-classes of diabetes. The next section deals with genetics and immunology. The third section discusses abnormalities of insulin secretion and act ion on both the receptor and post . . . receptor levels. The role of gastrointestinal peptides in Type I and Type II diabetes is also considered. In the last section, both types of diabetes are compared with respect to diabetic complications. The closing sec­ tion summarizes the present status and offers a stimulating view of future development. We hope that this book will be a useful source of information for both researchers and practicing clinicians. M. Vranic G. steiner C. H. Hollenberg v ACKNOWLEDGEMENTS The symposium from which this volume arose (June 28-29, 1984) was organized by the Banting and Best Diabetes Centre, University of Toronto. We would like to express our appreciation to the following sponsors: Ames Educational Institute, Ayerst Laboratories, Becton Dickinson Canada Inc. , Canadian Soft Drink Association, Connaught Laboratories Limited, Connaught Novo Ltd. , Eli Lilly Canada Inc.


Insulin Insulin Secretion diabetes

Editors and affiliations

  • Mladen Vranic
    • 1
  • Charles H. Hollenberg
    • 2
  • George Steiner
    • 1
    • 3
  1. 1.Departments of Physiology and Medicine and Banting and Best Diabetes CentreUniversity of TorontoTorontoCanada
  2. 2.Department of Medicine and Banting and Best Diabetes CentreUniversity of TorontoTorontoCanada
  3. 3.Division of Endocrinology and MetabolismToronto General HospitalTorontoCanada

Bibliographic information

  • Book Title Comparison of Type I and Type II Diabetes
  • Book Subtitle Similarities and Dissimilarities in Etiology, Pathogenesis, and Complications
  • Editors Mladen Vranic
  • Series Title Advances in Experimental Medicine and Biology
  • DOI
  • Copyright Information Springer-Verlag US 1985
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Hardcover ISBN 978-0-306-42066-5
  • Softcover ISBN 978-1-4757-1852-2
  • eBook ISBN 978-1-4757-1850-8
  • Series ISSN 0065-2598
  • Series E-ISSN 2214-8019
  • Edition Number 1
  • Number of Pages XI, 351
  • Number of Illustrations 75 b/w illustrations, 0 illustrations in colour
  • Topics Diabetes
  • Buy this book on publisher's site
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