Biological Response Modifiers in Human Oncology and Immunology

  • Thomas Klein
  • Steven Specter
  • Herman Friedman
  • Andor Szentivanyi

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 166)

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Introduction

    1. Yuichi Yamamura, Ichiro Azuma
      Pages 1-13
  3. Biological Response Modifiers Derived from Leukocytes

  4. Biological Response Modifiers Derived from Microorganisms

    1. Shozo Kotani, Ichiro Azuma, Haruhiko Takada, Masachika Tsujimoto, Yuichi Yamamura
      Pages 117-158
    2. Gerald Vosika, Tim Trenbeath, Cathy Giddings, Gary R. Gray
      Pages 159-169
    3. J. M. Lang, A. Aleksijevic, C. Giron, S. Levy, A. Falkenrodt, S. Mayer et al.
      Pages 171-180
    4. Tetsuo Taguchi, Hisashi Furue, Tadashi Kimura, Tatsuhei Kondo, Takao Hattori, Nobuya Ogawa
      Pages 181-187
    5. Michael J. Pabst, Nancy P. Cummings, Holly B. Hedegaard, Richard B. Johnston Jr.
      Pages 215-221
  5. Synthetic Biological Response Modifiers

    1. G. Renoux, M. Renoux, E. Lemarie, M. Lavandier, J. Greco, P. Bardos et al.
      Pages 223-239
    2. L. N. Simon, F. K. Hoehler, D. T. McKenzie, J. W. Hadden
      Pages 241-259
    3. R. Favre, D. Bagarry-Liegey, B. Jeanroy, T. Pignon, G. Meyer, Y. Carcassonne
      Pages 261-268
  6. Acquired Immunodeficiency Syndrome

    1. Evan M. Hersh, James M. Reuben, Peter W. A. Mansell, Adan Rios, Guy R. Newell, Jess Frank et al.
      Pages 285-293
  7. Workshop Summaries

  8. Back Matter
    Pages 317-320

About this book


The topic of biological response modifiers has attracted the attention of many biomedical investigators, including immunologists, oncologists, pharmacologists, microbiologists, and biochemists, as well as clinical practitioners of medicine. This has occurred mainly because of the realization that the complex system of cellular and humoral interactions culminating in a productive immune response is under exquisite regulatory control for normal immune responses and that loss of control may markedly influence the capability of a host to respond in a productive manner to the numerous immunologic "insults" encountered in the environment. Furthermore, biological response modification is considered by many to be a natural offshoot of the relatively new application of "immunotherapy" to cancer. It is widely recognized that "immunotherapy" was practiced at the end of the last century and the beginning of this century when it was recognized that microbial infections were caused by distinct species of bacteria and that passive administration of serum con­ taining antibody to these microbes or their products could, in many cases, favorably influence the outcome of an infectious process.


bacteria cancer cancer treatment cell chemotherapy immune response immunology immunotherapy interferon leukemia lymphocytes macrophages oncology pharmacology tumor

Editors and affiliations

  • Thomas Klein
    • 1
  • Steven Specter
    • 1
  • Herman Friedman
    • 1
  • Andor Szentivanyi
    • 1
  1. 1.University of South FloridaTampaUSA

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag US 1983
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4757-1412-8
  • Online ISBN 978-1-4757-1410-4
  • Series Print ISSN 0065-2598
  • Buy this book on publisher's site
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