The Physiology of Thirst and Sodium Appetite

  • G. de Caro
  • A. N. Epstein
  • M. Massi

Part of the NATO ASI Series book series (NSSA, volume 105)

Table of contents

  1. Front Matter
    Pages i-xx
  2. The Phylogeny and Ontogeny of Thirst

    1. D. A. Denton, M. J. McKinley, P. Osborne, Eva Tarjan, R. S. Weisinger
      Pages 1-12
    2. Priscilla Kehoe, Elliott M. Blass
      Pages 25-29
    3. Karen Moe
      Pages 31-36
    4. F. Cantalamessa, G. de Caro, A. N. Epstein, M. Perfumi
      Pages 37-42
  3. Drinking and Water Homeostasis

    1. L. Di Bella, M. T. Rossi
      Pages 59-64
    2. M. T. Rossi, L. Di Bella
      Pages 65-70
    3. Z. Arad, G. E. Rice, E. Skadhauge
      Pages 71-76
  4. Hyperosmotic and Hypovolemic Thirst

    1. David J. Ramsay, Terry N. Thrasher
      Pages 83-96
    2. Ewa Szczepańska-Sadowska, Jadwiga Sobocińska, Stanisław Kozłowski
      Pages 97-102
    3. Sandra P. Frankmann, Daniel M. Dorsa, Randall R. Sakai, John B. Simpson
      Pages 115-121
  5. Central Renin-Angiotensin System

    1. Thomas Unger, Detlev Ganten, Gerald Ludwig, Rudolf E. Lang
      Pages 123-133
    2. D. Felix, M. C. Gambino, Y. Yong, P. Schelling
      Pages 135-140
    3. J. W. Harding, R. H. Abhold, C. G. Camara, J. B. Erickson, E. P. Petersen
      Pages 141-147
    4. W. B. Severs, H. J. Spaeth, J. N. D. Wurpel, R. L. Dundore, R. T. Henry, L. C. Keil
      Pages 149-154
  6. Peripheral Renin-Angiotensin System

    1. Alan Kim Johnson, Marilyn M. Robinson, Johannes F. E. Mann
      Pages 161-180
    2. M. Costales, M. Vijande, B. Marín, J. I. Brime, P. Lopez-Sela
      Pages 181-186
    3. John W. Wright, Sandra L. Morseth, Margaret J. Sullivan, Joseph W. Harding
      Pages 187-192
    4. Marilyn M. Robinson, Mark D. Evered
      Pages 193-198
    5. Johannes F. E. Mann, Siegfried Eisele, Detlev Ganten, A. Kim Johnson, Rainer Rettig, Eberhard Ritz et al.
      Pages 199-203
  7. Brain Peptides and other Endogenous Substances

  8. Peripheral Mechanisms in Maintenance and Termination of Drinking

  9. The Nature and Localization of Central Receptor Systems

    1. M. J. McKinley, D. A. Denton, M. Leventer, R. R. Miselis, R. G. Park, E. Tarjan et al.
      Pages 321-326
    2. Terry N. Thrasher, David J. Ramsay
      Pages 327-332
    3. J. W. Harding, J. B. Erickson, J. W. Wright, C. G. Camara, R. H. Abhold
      Pages 333-338
  10. Neuroanatomical Circuitry

About this book


The behavioral neuroscience of thirst and sodium appetite are research ventures that have expanded dramatically in recent years. Work done in the mid-1950s and early 1960s made it clear that drinking behavior could be affected by direct manipulations of the brain, especially by brain damage and by pharmacological treat­ ments. Since that. time experimental approaches have diversified and the research enterprise has attracted the interest of a broad international community of scientists. Many aspects of both thirst and sodium appetite are being studied. The most prominent of these are: 1) phylogenetic and ontogenetic aspects of the phenomena of drink­ ing behavior, 2) the mechanisms of a variety of dipsogenic and antidipsogenic treatments, both drugs and hormones, 3) the biological controls of drinking and their interaction with the regulation of blood volume and blood pressure, 4) the peripheral signals of drinking including the role of the baro- and volume-receptors, 5) the receptor systems within the brain and the neuroanatomical circuitry for thirst and sodium appetite, and 6) the possible roles of brain sodium and of the hormones of sodium conservation ln the arousal of sodium appetite. This acceleration of basic research activity has given in­ sights into the clinical disorders of thirst and salt appetite and has produced pharmacological agents of potential therapeutic use.


Pet behavior biological brain conservation experiment neuroscience pharmacology physiology receptor receptors regulation sodium

Editors and affiliations

  • G. de Caro
    • 1
  • A. N. Epstein
    • 2
  • M. Massi
    • 1
  1. 1.University of CamerinoCamerinoItaly
  2. 2.University of PennsylvaniaPhiladelphiaUSA

Bibliographic information