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Elastin and Elastic Tissue

  • Book
  • © 1977

Overview

Editors:
  1. Lawrence B. Sandberg

    1. University of Utah, Salt Lake City, USA

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  2. William R. Gray

    1. University of Utah, Salt Lake City, USA

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  3. Carl Franzblau

    1. Boston University School of Medicine, Boston, USA

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Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 79)

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Table of contents (64 chapters)

  1. Turnover and Elastolysis in Elastic Tissue

    1. Proteolysis of Tropoelastin

      • Robert Mecham, Judith A. Foster, Carl Franzblau
      Pages 209-216

    2. Elastin Degradation in Human and Experimental Emphysema

      • Ines Mandl, T. V. Darnule, J. A. Fierer, S. Keller, Gerard M. Turino
      Pages 221-231

    3. The Fate of Intratracheal 14C-Guanidinated Pancreatic Elastase in Hamster Lung

      • P. J. Stone, V. Pereira, D. Biles, G. L. Snider, H. M. Kagan, C. Franzblau
      Pages 233-248

    4. Comparison of the Elastolytic Effects of Human Leukocyte Elastase and Porcine Pancreatic Elastase

      • Robert M. Senior, David R. Bielefeld, Barry C. Starcher
      Pages 249-258

    5. General Discussion on Turnover and Elastolysis

      • Lawrence B. Sandberg, William R. Gray, Carl Franzblau
      Pages 259-261

  2. Chemical Structure of Elastin

    1. Front Matter

      Pages 263-263
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    2. Introduction

      • Judith A. Foster
      Pages 265-265

    3. The Isolation and Amino Acid Sequence of Some Thrombin Produced Porcine Tropoelastin Peptides

      • A. R. Torres, V. L. Alvarez, L. B. Sandberg, W. R. Gray
      Pages 267-276

    4. Primary Structure of Porcine Tropoelastin

      • L. B. Sandberg, W. R. Gray, J. A. Foster, A. R. Torres, V. L. Alvarez, Jarmilla Janata
      Pages 277-284

    5. Some Kinetic Aspects of Crosslink Biosynthesis

      • W. R. Gray
      Pages 285-290

    6. Evolution of Elastin Structure

      • E. H. Sage, W. R. Gray
      Pages 291-312

    7. Role of Crosslinking in Fiber Formation

      • C. Franzblau, J. A. Foster, B. Faris
      Pages 313-327

    8. Desmosine Peptides: Amino Acid Sequences and the Role of These Sequences in Crosslink Formation

      • R. A. Anwar
      Pages 329-342

    9. Crosslinking Profiles of Elastin from Anatomically Defined Regions of the Lung

      • Mercedes A. Paz, David A. Keith, Paul M. Gallop
      Pages 343-350

    10. A High Molecular Weight Species of Soluble Elastin-Proelastin

      • Judith Ann Foster, Robert Mecham, Michael Imberman, Barbara Faris, Carl Franzblau
      Pages 351-369

  3. Elastin Biosynthesis and Metabolism

    1. Front Matter

      Pages 371-371
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    2. Introduction

      • R. B. Rucker
      Pages 373-374

    3. Studies on the Major Fucosylated Glycoprotein Released into the Medium by Cultured Human Skin Fibroblasts

      • Christopher H. J. Sear, Michael E. Grant, David S. Jackson
      Pages 375-384

    4. Studies of the Biosynthesis of a Soluble Precursor of Elastin

      • Don W. Smith, Pathrapamkel A. Abraham, William H. Carnes
      Pages 385-395

    5. The Biosynthesis of Elastin by an Aortic Medial Cell Culture

      • Pathrapamkel A. Abraham, Mary Lou Hart, A. Royce Winge, William H. Carnes
      Pages 397-412
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Keywords

About this book

Although elastin was first identified and purifled in 1840, relatively few, major advances to determine its structure and function occurred between then and 1970. This was pointed out by Carl Franzblau in his recent review (1). This sad state of affairs does not detract, however, from the importance of contributions made during the last 50 years; many of these are referred to in the various chapters that comprise this monograph. I would be remiss not to emphasize the pioneering work of S. M. Partridge, who, in 1955, reported on a technique to obtain virtually pure elastin. It was, indeed, a privilege to have the participation of Dr. Partridge in the First International Conference on Elastin, the proceedings of which constitute this volume. In 1974, the Division of Lung Diseases of the National Heart, Lung, and Blood Institute initiated a targeted research program on "Isolation and Purification of Lung Elastin". It was an asset to the program that it attracted eminent scientists who, in effect, stimulated a new wave of interest and activity in this neglected area of research. This resurgence of interest may have been due to the challenge of working with a tissue that presented difficulties which had in the past discour­ aged investigators. It soon became apparent that the research program initiated by the Division of Lung Diseases was attracting much interest and that many significant contributions would result from it.

Editors and Affiliations

  • University of Utah, Salt Lake City, USA

    Lawrence B. Sandberg, William R. Gray

  • Boston University School of Medicine, Boston, USA

    Carl Franzblau

Bibliographic Information

  • Book Title: Elastin and Elastic Tissue

  • Editors: Lawrence B. Sandberg, William R. Gray, Carl Franzblau

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-1-4684-9093-0

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 1977

  • Softcover ISBN: 978-1-4684-9095-4Published: 26 November 2012

  • eBook ISBN: 978-1-4684-9093-0Published: 06 December 2012

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: XV, 782

  • Topics: Biochemistry, general

  • Industry Sectors: Biotechnology, Consumer Packaged Goods, Pharma

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